Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 1.000 definitive 0.969 225 47 1949 2018
Entrez Id: 1670
Gene Symbol: DEFA5
DEFA5
Q01523 defensin alpha 5 19 0.743 0.345 5.9E-06 0.300 1 0 2008 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.050 1.000 5 0 2000 2013
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.050 1.000 5 0 1998 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.040 1.000 4 0 2002 2004
Entrez Id: 5568
Gene Symbol: PRKACG
PRKACG
P22612 protein kinase cAMP-activated catalytic subunit gamma 29 0.701 0.414 0.030 1.000 3 0 2000 2006
Entrez Id: 5127
Gene Symbol: CDK16
CDK16
Q00536 cyclin dependent kinase 16 kinase; transferase 29 0.696 0.414 0.99 0.030 1.000 3 0 2000 2006
Entrez Id: 9874
Gene Symbol: TLK1
TLK1
Q9UKI8 tousled like kinase 1 kinase; transferase 25 0.713 0.414 1.00 0.030 1.000 3 0 2000 2006
Entrez Id: 22858
Gene Symbol: ICK
ICK
Q9UPZ9 intestinal cell kinase kinase; transferase 88 0.602 0.621 6.7E-06 0.030 1.000 3 0 2000 2006
Entrez Id: 55872
Gene Symbol: PBK
PBK
Q96KB5 PDZ binding kinase kinase; transferase 61 0.607 0.621 7.7E-06 0.030 1.000 3 0 2000 2006
Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14
Q99558 mitogen-activated protein kinase kinase kinase 14 38 0.648 0.552 0.030 1.000 3 0 2000 2006
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase kinase; nucleic acid binding; transferase 466 0.399 0.793 1.00 0.030 1.000 3 0 2005 2011
Entrez Id: 65061
Gene Symbol: CDK15
CDK15
Q96Q40 cyclin dependent kinase 15 kinase; transferase 19 0.727 0.448 1.4E-17 0.030 1.000 3 0 2000 2006
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 nucleic acid binding 212 0.503 0.759 1.00 0.020 1.000 2 0 2001 2005
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.020 0.500 2 0 2001 2001
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.020 1.000 2 0 1999 2013
Entrez Id: 4629
Gene Symbol: MYH11
MYH11
P35749 myosin heavy chain 11 99 0.567 0.483 0.88 0.020 1.000 2 0 2008 2008
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II oxidoreductase 494 0.397 0.862 0.020 1.000 2 0 2003 2004
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
P49815 TSC complex subunit 2 enzyme modulator 290 0.463 0.690 1.00 0.020 1.000 2 0 2004 2006
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
P20813 cytochrome P450 family 2 subfamily B member 6 306 0.437 0.828 3.5E-10 0.020 1.000 2 0 1994 1994
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 349 0.466 0.690 1.00 0.020 1.000 2 0 2010 2011
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 nucleic acid binding; receptor; transcription factor 263 0.455 0.793 6.2E-09 0.010 1.000 1 0 2008 2008
Entrez Id: 8500
Gene Symbol: PPFIA1
PPFIA1
Q13136 PTPRF interacting protein alpha 1 9 0.815 0.138 1.00 0.010 1.000 1 0 2002 2002
Entrez Id: 11140
Gene Symbol: CDC37
CDC37
Q16543 cell division cycle 37 chaperone; enzyme modulator 17 0.727 0.310 0.90 0.010 1.000 1 0 2004 2004
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1
Prader Willi/Angelman region RNA 1 164 0.528 0.690 0.010 1.000 1 0 2008 2008