Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.966 59 1 1998 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.942 52 0 2006 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 0.980 50 0 2002 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 49 1 2002 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.600 None 0.975 40 0 1995 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.400 None 1.000 33 0 2007 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.100 None 1.000 30 0 2000 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 1.000 29 0 1996 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.400 None 1.000 28 2 2002 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 19 0 2011 2020
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.400 None 1.000 18 0 2011 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.100 None 0.941 17 3 2012 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.200 None 0.933 15 3 2004 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 0.933 15 0 2004 2019
Entrez Id: 3596
Gene Symbol: IL13
IL13
P35225 interleukin 13 587 0.386 0.846 1.4E-02 0.400 None 0.929 14 0 2002 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.923 13 0 2002 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.400 None 1.000 13 0 2010 2019
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
P11226 mannose binding lectin 2 Receptor 563 0.390 0.846 2.7E-03 0.100 None 1.000 13 0 2004 2018
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.100 None 1.000 13 0 2001 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 0.917 12 0 2012 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.400 None 0.917 12 0 2009 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 12 0 2006 2019
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
Q92581 solute carrier family 9 member A6 Transporter 210 0.516 0.846 1.00 0.100 None 1.000 10 0 2009 2019
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
P09341 C-X-C motif chemokine ligand 1 Signaling 315 0.449 0.923 0.12 0.580 None 1.000 10 0 1996 2019
Entrez Id: 3567
Gene Symbol: IL5
IL5
P05113 interleukin 5 359 0.437 0.846 5.7E-03 0.100 None 1.000 10 0 2001 2019