Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.090 None 1.000 9 0 1999 2019
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 340 0.461 0.808 0.15 0.090 None 1.000 9 0 2001 2018
Entrez Id: 7905
Gene Symbol: REEP5
REEP5
Q00765 receptor accessory protein 5 Transporter 49 0.633 0.615 7.0E-04 0.080 None 1.000 8 0 1993 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.370 None 1.000 8 0 1993 2019
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
P14555 phospholipase A2 group IIA Enzyme 215 0.488 0.808 9.7E-02 0.080 None 0.875 8 0 1996 2007
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.080 None 0.875 8 0 2003 2010
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.070 None 1.000 7 0 2007 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.070 None 1.000 7 0 1998 2017
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
P11926 ornithine decarboxylase 1 Enzyme 184 0.510 0.731 0.17 0.060 None 1.000 6 0 1984 2011
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.060 None 0.833 6 0 1998 2017
Entrez Id: 6925
Gene Symbol: TCF4
TCF4
P15884 transcription factor 4 Transcription factor 378 0.464 0.846 1.00 0.060 None 1.000 6 0 1999 2008
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.060 None 1.000 6 0 2003 2011
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.060 None 0.833 6 0 2012 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.060 None 0.833 6 1 2004 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.060 None 1.000 6 1 1995 2019
Entrez Id: 4913
Gene Symbol: NTHL1
NTHL1
P78549 nth like DNA glycosylase 1 Enzyme 57 0.623 0.615 5.7E-10 0.360 None 1.000 6 1 2015 2019
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.350 None 1.000 5 0 1998 2019
Entrez Id: 22919
Gene Symbol: MAPRE1
MAPRE1
Q15691 microtubule associated protein RP/EB family member 1 Cellular structure 35 0.674 0.462 0.99 0.050 None 1.000 5 0 1998 2014
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
Q16204 coiled-coil domain containing 6 156 0.517 0.808 0.58 0.050 None 0.800 5 0 1998 2019
Entrez Id: 8658
Gene Symbol: TNKS
TNKS
O95271 tankyrase 88 0.576 0.692 1.1E-02 0.050 None 1.000 5 0 2016 2020
Entrez Id: 5915
Gene Symbol: RARB
RARB
P10826 retinoic acid receptor beta Nuclear receptor 254 0.478 0.846 1.00 0.050 None 1.000 5 0 2004 2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.050 None 1.000 5 0 2014 2019
Entrez Id: 50649
Gene Symbol: ARHGEF4
ARHGEF4
Q9NR80 Rho guanine nucleotide exchange factor 4 13 0.839 0.269 7.4E-04 0.050 None 1.000 5 0 2006 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 257 0.485 0.846 1.00 0.050 None 1.000 5 0 1999 2008
Entrez Id: 51176
Gene Symbol: LEF1
LEF1
Q9UJU2 lymphoid enhancer binding factor 1 211 0.486 0.769 1.00 0.050 None 1.000 5 0 2002 2007