Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		P02545 lamin A/C 824 0.384 0.885 1.00 1.000 None 0.967 213 34 2003 2020
Entrez Id: 10269
Gene Symbol: ZMPSTE24
ZMPSTE24 		O75844 zinc metallopeptidase STE24 Enzyme 265 0.517 0.731 8.9E-16 0.800 None 0.967 30 0 2002 2019
Entrez Id: 5831
Gene Symbol: PYCR1
PYCR1 		P32322 pyrroline-5-carboxylate reductase 1 126 0.570 0.654 2.0E-04 0.310 None 1.000 2 0 2009 2018
Entrez Id: 288
Gene Symbol: ANK3
ANK3 		Q12955 ankyrin 3 106 0.578 0.654 1.00 0.310 None 1.000 2 0 2006 2016
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN 		Q9H040 SprT-like N-terminal domain 44 0.691 0.500 0.97 0.300 None 1.000 1 0 2014 2014
Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6 		Q8N6T7 sirtuin 6 Epigenetic regulator 195 0.496 0.846 3.9E-02 0.200 None 1.000 2 0 2006 2015
Entrez Id: 64221
Gene Symbol: ROBO3
ROBO3 		Q96MS0 roundabout guidance receptor 3 Receptor 154 0.520 0.808 2.0E-15 0.040 None 1.000 4 0 2004 2013
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4 		Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 325 0.468 0.846 1.4E-12 0.040 None 1.000 4 2 2007 2015
Entrez Id: 55226
Gene Symbol: NAT10
NAT10 		Q9H0A0 N-acetyltransferase 10 133 0.536 0.769 4.1E-22 0.030 None 1.000 3 0 2018 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.030 None 1.000 3 0 2010 2018
Entrez Id: 7486
Gene Symbol: WRN
WRN 		Q14191 WRN RecQ like helicase Enzyme 172 0.524 0.808 2.6E-34 0.030 None 1.000 3 0 2012 2018
Entrez Id: 23353
Gene Symbol: SUN1
SUN1 		O94901 Sad1 and UNC84 domain containing 1 Cellular structure 26 0.729 0.423 9.2E-06 0.030 None 1.000 3 0 2012 2014
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.030 None 1.000 3 0 2016 2019
Entrez Id: 7507
Gene Symbol: XPA
XPA 		P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 209 0.520 0.846 7.9E-05 0.030 None 1.000 3 0 2008 2017
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.030 None 1.000 3 0 2016 2019
Entrez Id: 8815
Gene Symbol: BANF1
BANF1 		O75531 BAF nuclear assembly factor 1 86 0.599 0.692 0.65 0.030 None 1.000 3 0 2012 2019
Entrez Id: 653590
Gene Symbol: GGTLC5P
GGTLC5P 		gamma-glutamyltransferase light chain 5 pseudogene 165 0.513 0.846 0.020 None 1.000 2 0 2003 2009
Entrez Id: 5319
Gene Symbol: PLA2G1B
PLA2G1B 		P04054 phospholipase A2 group IB Enzyme 268 0.468 0.846 1.0E-10 0.020 None 1.000 2 0 2018 2019
Entrez Id: 728226
Gene Symbol: GGTLC3
GGTLC3 		B5MD39 gamma-glutamyltransferase light chain family member 3 165 0.513 0.846 0.020 None 1.000 2 0 2003 2009
Entrez Id: 2678
Gene Symbol: GGT1
GGT1 		P19440 gamma-glutamyltransferase 1 Enzyme 209 0.496 0.885 7.5E-05 0.020 None 1.000 2 0 2003 2009
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.020 None 1.000 2 0 1992 2007
Entrez Id: 3621
Gene Symbol: ING1
ING1 		Q9UK53 inhibitor of growth family member 1 Nucleic acid binding 99 0.573 0.692 9.7E-03 0.020 None 1.000 2 0 2008 2017
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B 		O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 231 0.502 0.808 7.0E-10 0.020 None 1.000 2 0 2018 2020
Entrez Id: 4001
Gene Symbol: LMNB1
LMNB1 		P20700 lamin B1 128 0.564 0.731 0.55 0.020 None 0.500 2 0 2011 2013
Entrez Id: 270
Gene Symbol: AMPD1
AMPD1 		P23109 adenosine monophosphate deaminase 1 Enzyme 106 0.573 0.692 1.9E-21 0.020 None 1.000 2 0 2014 2018