Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.400 None 0.988 82 0 1991 2019
Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
O15393 transmembrane serine protease 2 Enzyme 69 0.615 0.500 2.4E-10 0.400 None 0.970 33 0 2001 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.400 None 1.000 31 0 2000 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 31 0 1994 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 1.000 30 0 2000 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.400 None 1.000 27 0 1997 2017
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
P31213 steroid 5 alpha-reductase 2 Enzyme 106 0.564 0.615 0.400 None 1.000 26 0 2000 2015
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
Q04609 folate hydrolase 1 Enzyme 311 0.453 0.885 6.2E-09 0.400 None 1.000 25 0 1997 2020
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.400 None 1.000 25 0 2001 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.400 None 0.960 25 0 1997 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.400 None 1.000 22 0 2002 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.600 None 1.000 20 0 2002 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.400 None 1.000 20 0 1999 2018
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.400 None 1.000 19 0 2002 2015
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.400 None 1.000 19 0 2002 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 18 0 2002 2019
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.400 None 1.000 17 0 1997 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 17 0 2000 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.400 None 1.000 16 0 1990 2009
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.400 None 1.000 16 0 2002 2017
Entrez Id: 23600
Gene Symbol: AMACR
AMACR
Q9UHK6 alpha-methylacyl-CoA racemase 179 0.510 0.769 2.7E-02 0.400 None 1.000 16 0 2002 2015
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.400 None 1.000 16 0 2002 2014
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
Q99801 NK3 homeobox 1 Transcription factor 22 0.722 0.269 4.7E-04 0.600 None 1.000 16 0 1999 2013
Entrez Id: 9189
Gene Symbol: ZBED1
ZBED1
O96006 zinc finger BED-type containing 1 33 0.716 0.423 3.6E-04 0.400 None 1.000 16 0 2003 2019
Entrez Id: 1805
Gene Symbol: DPT
DPT
Q07507 dermatopontin Extracellular structure 60 0.641 0.654 4.3E-06 0.100 None 1.000 15 0 2003 2019