Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.100 None 1.000 25 0 1993 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.100 None 1.000 16 0 1987 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 1.000 12 0 1998 2018
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
P98161 polycystin 1, transient receptor potential channel interacting 217 0.493 0.769 1.00 0.100 None 1.000 11 0 1992 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.380 None 1.000 9 1 1997 2015
Entrez Id: 4627
Gene Symbol: MYH9
MYH9
P35579 myosin heavy chain 9 196 0.505 0.808 1.00 0.380 strong 1.000 9 4 2004 2017
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.080 None 1.000 8 0 2013 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.080 None 1.000 8 1 1998 2013
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
P80188 lipocalin 2 Enzyme 497 0.405 0.885 1.1E-09 0.080 None 1.000 8 0 2010 2019
Entrez Id: 8542
Gene Symbol: APOL1
APOL1
O14791 apolipoprotein L1 Transporter 115 0.547 0.615 5.1E-06 0.070 None 1.000 7 0 2011 2018
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP
Q9Y5K6 CD2 associated protein 113 0.558 0.731 0.23 0.070 None 1.000 7 0 2003 2017
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.070 None 1.000 7 0 1987 2011
Entrez Id: 9771
Gene Symbol: RAPGEF5
RAPGEF5
Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 151 0.524 0.769 0.98 0.070 None 1.000 7 0 2003 2019
Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
O43707 actinin alpha 4 166 0.508 0.808 1.00 0.060 None 1.000 6 0 2008 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.350 None 1.000 6 0 1998 2014
Entrez Id: 1184
Gene Symbol: CLCN5
CLCN5
P51795 chloride voltage-gated channel 5 Ion channel 101 0.593 0.577 0.99 0.050 None 1.000 5 2 1998 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.050 None 1.000 5 0 2004 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.050 None 1.000 5 0 1999 2015
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.330 None 1.000 5 0 1986 2018
Entrez Id: 60498
Gene Symbol: IGAN1
IGAN1
IgA nephropathy 140 0.524 0.808 0.050 None 1.000 5 0 2005 2019
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.040 None 1.000 4 0 2010 2020
Entrez Id: 567
Gene Symbol: B2M
B2M
P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.040 None 1.000 4 0 2009 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.040 None 1.000 4 0 2018 2020
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.040 None 1.000 4 0 1999 2020
Entrez Id: 846
Gene Symbol: CASR
CASR
P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.040 None 1.000 4 1 2002 2017