Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.800 None 0.986 214 157 1984 2020
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4 regulator of p53 Nucleic acid binding 265 0.461 0.808 1.00 0.400 None 1.000 10 1 2006 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
Q6W2J9 BCL6 corepressor 314 0.471 0.808 1.00 0.310 None 1.000 1 0 2014 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 0.960 275 2 1990 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.170 None 0.750 8 1 1995 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.110 None 1.000 1 0 2011 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 0.958 120 0 1993 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.100 None 0.962 79 0 1994 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.957 69 1 1991 2020
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
Q01094 E2F transcription factor 1 Nucleic acid binding 324 0.441 0.846 0.99 0.100 None 0.953 43 0 1996 2020
Entrez Id: 5934
Gene Symbol: RBL2
RBL2
Q08999 RB transcriptional corepressor like 2 Nucleic acid binding 89 0.579 0.769 1.00 0.100 None 1.000 41 2 1994 2018
Entrez Id: 2098
Gene Symbol: ESD
ESD
P10768 esterase D Enzyme 48 0.656 0.615 5.4E-07 0.100 None 0.947 38 0 1980 2009
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.100 None 0.972 36 0 1995 2019
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 314 0.454 0.808 0.89 0.100 None 0.969 32 0 1984 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.100 None 1.000 31 2 1996 2018
Entrez Id: 84260
Gene Symbol: TCHP
TCHP
Q9BT92 trichoplein keratin filament binding 90 0.570 0.692 1.8E-16 0.100 None 0.968 31 0 1992 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 0.963 27 0 2006 2019
Entrez Id: 5933
Gene Symbol: RBL1
RBL1
P28749 RB transcriptional corepressor like 1 Nucleic acid binding 40 0.666 0.385 2.9E-12 0.100 None 1.000 25 0 1992 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 0.917 24 0 1991 2019
Entrez Id: 22930
Gene Symbol: RAB3GAP1
RAB3GAP1
Q15042 RAB3 GTPase activating protein catalytic subunit 1 138 0.566 0.692 1.5E-07 0.100 None 1.000 23 0 1994 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 0.957 23 0 2007 2019
Entrez Id: 9221
Gene Symbol: NOLC1
NOLC1
Q14978 nucleolar and coiled-body phosphoprotein 1 47 0.641 0.615 1.0E-04 0.100 None 1.000 23 0 1994 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 0.957 23 0 2007 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 0.957 23 0 2007 2019
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
P24941 cyclin dependent kinase 2 Kinase 270 0.456 0.692 0.61 0.100 None 0.952 21 0 1996 2019