Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 49
Gene Symbol: ACR
ACR
P10323 acrosin Enzyme 230 0.493 0.846 1.2E-02 0.100 None 1.000 16 0 2006 2020
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.100 None 0.933 15 0 2002 2020
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.500 None 1.000 15 3 2009 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.846 13 0 2005 2020
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.100 None 1.000 13 1 1997 2019
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 504 0.407 0.885 8.9E-03 0.400 None 1.000 13 0 1992 2015
Entrez Id: 26039
Gene Symbol: SS18L1
SS18L1
O75177 SS18L1 subunit of BAF chromatin remodeling complex Nucleic acid binding 35 0.670 0.538 0.98 0.100 None 0.909 11 0 1983 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.909 11 1 2002 2020
Entrez Id: 55599
Gene Symbol: RNPC3
RNPC3
Q96LT9 RNA binding region (RNP1, RRM) containing 3 73 0.608 0.731 2.0E-04 0.100 None 0.909 11 0 1987 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.100 None 0.909 11 0 1995 2019
Entrez Id: 2355
Gene Symbol: FOSL2
FOSL2
P15408 FOS like 2, AP-1 transcription factor subunit Transcription factor 83 0.595 0.692 0.98 0.300 None 1.000 11 0 2010 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.100 None 1.000 10 0 2008 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.190 None 0.800 10 2 2006 2019
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
P01562 interferon alpha 13 646 0.374 0.923 0.090 None 1.000 9 0 1986 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
P01562 interferon alpha 1 662 0.371 0.923 0.090 None 1.000 9 0 1986 2019
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 324 0.453 0.923 5.3E-10 0.180 None 1.000 9 3 1996 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.090 None 0.778 9 2 2010 2020
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.090 None 1.000 9 0 1990 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.090 None 1.000 9 1 2003 2018
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
P11387 DNA topoisomerase I Enzyme 143 0.542 0.692 1.00 0.090 None 0.889 9 0 1989 2018
Entrez Id: 919
Gene Symbol: CD247
CD247
P20963 CD247 molecule 140 0.539 0.731 1.7E-02 0.460 None 0.875 8 1 1998 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.080 None 0.875 8 1 2002 2019
Entrez Id: 10950
Gene Symbol: BTG3
BTG3
Q14201 BTG anti-proliferation factor 3 141 0.528 0.808 0.92 0.080 None 0.875 8 0 1994 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.080 None 0.875 8 1 2000 2017
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B
Q9Y275 TNF superfamily member 13b 282 0.460 0.731 0.98 0.080 None 0.875 8 1 2007 2018