Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.500 None 0.955 179 4 1980 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.910 145 3 1991 2020
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 156 0.556 0.692 2.1E-26 0.500 None 0.979 95 24 2007 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.944 71 2 1991 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 1.000 63 1 2009 2020
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.500 None 0.964 55 19 2007 2019
Entrez Id: 51561
Gene Symbol: IL23A
IL23A
Q9NPF7 interleukin 23 subunit alpha Signaling 427 0.415 0.846 0.36 0.100 None 0.968 31 0 2009 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 0.920 25 6 2001 2020
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
P10321 major histocompatibility complex, class I, C 435 0.415 0.846 1.6E-06 0.100 None 0.952 21 0 2000 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.900 20 3 2001 2020
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
P43629 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Receptor 231 0.475 0.769 8.4E-14 0.100 None 0.895 19 0 2006 2019
Entrez Id: 64167
Gene Symbol: ERAP2
ERAP2
Q6P179 endoplasmic reticulum aminopeptidase 2 Enzyme 58 0.615 0.577 1.0E-28 0.200 None 0.882 17 5 2010 2019
Entrez Id: 56246
Gene Symbol: MRAP
MRAP
Q8TCY5 melanocortin 2 receptor accessory protein 51 0.674 0.500 2.1E-03 0.100 None 0.875 16 0 1978 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.200 None 0.933 15 3 2001 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.100 None 0.929 14 0 1997 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.200 None 0.786 14 2 2005 2019
Entrez Id: 27178
Gene Symbol: IL37
IL37
Q9NZH6 interleukin 37 280 0.459 0.846 1.2E-04 0.100 None 1.000 14 1 2009 2019
Entrez Id: 22943
Gene Symbol: DKK1
DKK1
O94907 dickkopf WNT signaling pathway inhibitor 1 372 0.439 0.885 0.17 0.100 None 1.000 14 1 2014 2020
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.200 None 1.000 14 6 2005 2019
Entrez Id: 2669
Gene Symbol: GEM
GEM
P55040 GTP binding protein overexpressed in skeletal muscle 251 0.467 0.769 1.2E-08 0.100 None 0.923 13 0 2008 2019
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
P58335 ANTXR cell adhesion molecule 2 Receptor 143 0.568 0.808 8.7E-02 0.500 None 0.833 12 7 2010 2018
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.200 None 1.000 12 5 2008 2019
Entrez Id: 50964
Gene Symbol: SOST
SOST
Q9BQB4 sclerostin 270 0.474 0.808 0.87 0.100 None 0.909 11 0 2017 2020
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.100 None 1.000 11 2 2004 2019
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
P29460 interleukin 12B Signaling 249 0.480 0.885 1.1E-04 0.400 None 1.000 10 1 2007 2019