Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.600 None 1.000 31 0 1998 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 24 0 1999 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.955 22 0 2001 2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.400 None 1.000 20 0 2002 2016
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
Q13761 RUNX family transcription factor 3 Transcription factor 281 0.459 0.731 0.84 0.400 None 1.000 16 0 2003 2012
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 1.000 14 0 2002 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.390 None 1.000 12 0 1995 2017
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.370 None 1.000 11 0 1995 2009
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 11 0 2004 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 11 0 2003 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.580 None 1.000 10 0 2004 2019
Entrez Id: 7031
Gene Symbol: TFF1
TFF1
P04155 trefoil factor 1 Signaling 147 0.529 0.769 8.9E-04 0.280 None 1.000 9 0 2002 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.090 None 1.000 9 0 2003 2008
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.080 None 1.000 8 0 2002 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.360 None 1.000 8 0 1992 2013
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 Enzyme modulator 199 0.495 0.731 5.6E-02 0.370 None 1.000 8 0 2002 2008
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
P40189 interleukin 6 signal transducer Signaling 260 0.475 0.808 1.00 0.220 None 1.000 7 0 2002 2014
Entrez Id: 30834
Gene Symbol: ZNRD1
ZNRD1
Q9P1U0 zinc ribbon domain containing 1 50 0.653 0.654 0.21 0.360 None 1.000 7 0 2004 2008
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.070 None 1.000 7 0 2003 2015
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.370 None 1.000 7 0 2002 2008
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.170 None 1.000 7 0 2000 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.060 None 1.000 6 0 2002 2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.450 None 1.000 6 0 1997 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.350 None 1.000 6 0 2006 2011
Entrez Id: 56287
Gene Symbol: GKN1
GKN1
Q9NS71 gastrokine 1 55 0.628 0.615 1.1E-06 0.350 None 1.000 6 0 2004 2019