Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.500 0.906 95 3 1997 2017
Entrez Id: 2153
Gene Symbol: F5
F5
P12259 coagulation factor V cell adhesion molecule; hydrolase; receptor; signaling molecule 259 0.468 0.690 5.6E-15 0.500 0.867 40 1 1995 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.500 0.963 32 1 1989 2014
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
Q9UKV0 histone deacetylase 9 162 0.501 0.759 1.00 0.500 1.000 12 4 2012 2017
Entrez Id: 463
Gene Symbol: ZFHX3
ZFHX3
Q15911 zinc finger homeobox 3 51 0.656 0.517 1.00 0.460 1.000 8 2 2012 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type hydrolase; protease 267 0.459 0.828 3.5E-05 0.400 0.692 75 0 1990 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.400 0.811 54 0 1994 2017
Entrez Id: 5144
Gene Symbol: PDE4D
PDE4D
Q08499 phosphodiesterase 4D 168 0.572 0.690 1.00 0.400 0.938 37 5 2002 2017
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin hydrolase; protease 249 0.466 0.793 1.1E-03 0.400 0.923 29 1 1995 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.909 27 2 1999 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 0.875 27 1 1996 2016
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 475 0.398 0.897 3.4E-02 0.400 0.917 15 1 1995 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 12 0 2004 2016
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
P05106 integrin subunit beta 3 cell adhesion molecule; extracellular matrix protein; receptor 175 0.507 0.690 2.2E-03 0.400 0.889 12 0 1998 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.370 1.000 8 0 2000 2016
Entrez Id: 3674
Gene Symbol: ITGA2B
ITGA2B
P08514 integrin subunit alpha 2b 108 0.548 0.517 1.3E-15 0.360 0.400 7 0 1997 2012
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
Q13093 phospholipase A2 group VII hydrolase 75 0.584 0.552 8.9E-22 0.360 1.000 7 1 1998 2012
Entrez Id: 5308
Gene Symbol: PITX2
PITX2
Q99697 paired like homeodomain 2 197 0.510 0.724 0.98 0.350 1.000 6 0 2012 2018
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 531 0.385 0.931 1.5E-14 0.350 1.000 6 0 1999 2012
Entrez Id: 79001
Gene Symbol: VKORC1
VKORC1
Q9BQB6 vitamin K epoxide reductase complex subunit 1 oxidoreductase 59 0.639 0.655 0.16 0.350 1.000 5 1 2006 2016
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 148 0.530 0.690 1.3E-10 0.350 0.800 5 0 2003 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.340 1.000 5 0 2003 2016
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 signaling molecule 419 0.417 0.828 0.46 0.330 1.000 4 2 2003 2010
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
P39900 matrix metallopeptidase 12 hydrolase; protease 134 0.516 0.862 0.330 1.000 4 0 2004 2018
Entrez Id: 28
Gene Symbol: ABO
ABO
P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase transferase 193 0.491 0.828 0.330 1.000 4 0 2009 2018