Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2022
Gene Symbol: ENG
ENG 		P17813 endoglin 371 0.446 0.846 1.00 1.000 definitive 0.991 117 81 1994 2019
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1 		P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.600 None 1.000 73 0 1996 2019
Entrez Id: 2658
Gene Symbol: GDF2
GDF2 		Q9UK05 growth differentiation factor 2 Signaling 152 0.529 0.731 2.5E-03 0.540 None 1.000 5 0 2012 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.400 strong 1.000 17 0 2004 2019
Entrez Id: 6590
Gene Symbol: SLPI
SLPI 		P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.100 None 1.000 29 0 1996 2018
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2 		Q13873 bone morphogenetic protein receptor type 2 Kinase 146 0.538 0.654 1.00 0.080 None 1.000 8 0 2004 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.070 None 0.857 7 0 2005 2020
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3 		O14649 potassium two pore domain channel subfamily K member 3 Ion channel 93 0.584 0.654 0.90 0.020 None 1.000 2 0 2014 2018
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.020 None 1.000 2 0 2010 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.020 None 1.000 2 0 2014 2018
Entrez Id: 5784
Gene Symbol: PTPN14
PTPN14 		Q15678 protein tyrosine phosphatase non-receptor type 14 48 0.638 0.615 0.22 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5806
Gene Symbol: PTX3
PTX3 		P26022 pentraxin 3 296 0.457 0.808 7.0E-05 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5921
Gene Symbol: RASA1
RASA1 		P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7056
Gene Symbol: THBD
THBD 		P07204 thrombomodulin 303 0.457 0.769 5.4E-02 0.010 None 1.000 1 0 2006 2006
Entrez Id: 6334
Gene Symbol: SCN8A
SCN8A 		Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 302 0.510 0.731 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2 		P61812 transforming growth factor beta 2 Signaling 389 0.433 0.885 1.00 0.010 None 1.000 1 0 2004 2004
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2016 2016
Entrez Id: 842
Gene Symbol: CASP9
CASP9 		P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2018 2018