Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.943 35 0 1991 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 20 0 2003 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 1.000 20 0 1996 2017
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.100 None 1.000 17 0 1999 2019
Entrez Id: 2313
Gene Symbol: FLI1
FLI1 		Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 318 0.468 0.692 0.99 0.100 None 1.000 16 0 2010 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.100 None 1.000 16 0 1994 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 1.000 13 0 2003 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.100 None 1.000 11 0 2005 2019
Entrez Id: 2022
Gene Symbol: ENG
ENG 		P17813 endoglin 371 0.446 0.846 1.00 0.100 None 1.000 11 0 1997 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.909 11 0 1997 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 0.900 10 0 2009 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.100 None 1.000 10 0 2000 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.090 None 1.000 9 0 2003 2018
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.090 None 1.000 9 0 2007 2019
Entrez Id: 177
Gene Symbol: AGER
AGER 		Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.090 None 1.000 9 0 1996 2019
Entrez Id: 4973
Gene Symbol: OLR1
OLR1 		P78380 oxidized low density lipoprotein receptor 1 133 0.544 0.769 7.2E-03 0.080 None 1.000 8 0 2001 2019
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.080 None 1.000 8 0 2000 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.080 None 1.000 8 0 2007 2019
Entrez Id: 875
Gene Symbol: CBS
CBS 		P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.070 None 1.000 7 0 1996 2017
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2 		P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 287 0.469 0.846 0.84 0.070 None 1.000 7 0 2011 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA 		P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.070 None 0.857 7 0 1995 2019
Entrez Id: 1666
Gene Symbol: DECR1
DECR1 		Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.070 None 1.000 7 0 2010 2019
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2 		P62736 actin alpha 2, smooth muscle Cellular structure 200 0.508 0.846 0.93 0.070 None 1.000 7 0 2009 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.060 None 1.000 6 0 1999 2019
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		P18146 early growth response 1 Nucleic acid binding 378 0.433 0.923 0.35 0.060 None 1.000 6 0 2007 2019