Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.060 None 1.000 6 0 1992 2000
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.010 None 1.000 1 0 2016 2016
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 1 2005 2005
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.020 None 1.000 2 0 2003 2007
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.300 None 1.000 1 0 2010 2010
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.300 None 1.000 1 0 2006 2006
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		Q03164 lysine methyltransferase 2A 535 0.410 0.885 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 811
Gene Symbol: CALR
CALR 		P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.020 None 0.500 2 0 2016 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B 		P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.010 None 1.000 1 0 2014 2014
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.010 None 1.000 1 0 2004 2004
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1 		P04629 neurotrophic receptor tyrosine kinase 1 Kinase 443 0.422 0.808 2.0E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 9518
Gene Symbol: GDF15
GDF15 		Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.010 None 1.000 1 0 2012 2012
Entrez Id: 567
Gene Symbol: B2M
B2M 		P61769 beta-2-microglobulin Immune response 352 0.447 0.846 0.56 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.010 None 1.000 1 0 2015 2015
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1 		Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 321 0.459 0.808 8.9E-10 0.010 None 1.000 1 0 2014 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.010 None 1.000 1 0 2007 2007
Entrez Id: 799
Gene Symbol: CALCR
CALCR 		P30988 calcitonin receptor G-protein coupled receptor 282 0.464 0.846 3.1E-09 0.020 None 0.500 2 0 2016 2019
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3 		P35638 DNA damage inducible transcript 3 264 0.467 0.846 0.59 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.010 None 1.000 1 0 2012 2012