Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.500 None 0.971 68 1 1996 2019
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.500 None 1.000 45 7 1992 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 370 0.436 0.808 3.9E-03 0.170 None 1.000 7 1 1995 2017
Entrez Id: 9445
Gene Symbol: ITM2B
ITM2B 		Q9Y287 integral membrane protein 2B 77 0.617 0.654 0.63 0.120 None 0.500 2 0 2008 2009
Entrez Id: 10194
Gene Symbol: TSHZ1
TSHZ1 		Q6ZSZ6 teashirt zinc finger homeobox 1 Transcription factor 99 0.569 0.731 1.00 0.100 None 1.000 12 0 2008 2020
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2 		Q92692 nectin cell adhesion molecule 2 106 0.575 0.769 0.97 0.100 None 1.000 1 1 2014 2014
Entrez Id: 51112
Gene Symbol: TRAPPC12
TRAPPC12 		Q8WVT3 trafficking protein particle complex 12 Enzyme 28 0.751 0.385 5.4E-16 0.100 None 1.000 1 1 2018 2018
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		Q9UKV0 histone deacetylase 9 Epigenetic regulator 340 0.439 0.846 1.00 0.100 None 1.000 1 1 2018 2018
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		P49810 presenilin 2 Enzyme 146 0.550 0.654 5.4E-04 0.100 None 0 0
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.070 None 1.000 7 0 2002 2017
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.070 None 1.000 7 2 1997 2018
Entrez Id: 7276
Gene Symbol: TTR
TTR 		P02766 transthyretin Transporter 461 0.423 0.885 0.52 0.050 None 1.000 5 3 1991 2016
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.040 None 0.750 4 0 1996 2015
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.030 None 1.000 3 0 2010 2016
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.030 None 1.000 3 0 2004 2017
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2 		Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.030 None 1.000 3 0 2014 2020
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.030 None 1.000 3 0 2017 2019
Entrez Id: 4155
Gene Symbol: MBP
MBP 		P02686 myelin basic protein 184 0.510 0.885 0.28 0.020 None 1.000 2 1 2007 2009
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.020 None 1.000 2 1 2005 2012
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.020 None 1.000 2 0 2002 2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2 		Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.020 None 1.000 2 0 2017 2018
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.020 None 1.000 2 0 2017 2018
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.020 None 1.000 2 0 2002 2007
Entrez Id: 23621
Gene Symbol: BACE1
BACE1 		P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.020 None 1.000 2 0 2015 2016
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.020 None 1.000 2 0 2017 2019