Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.100 None 1.000 27 4 1994 2020
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.100 None 1.000 23 2 1999 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 17 2 2005 2020
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.100 None 1.000 14 0 2013 2019
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.100 None 1.000 11 4 2012 2019
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.100 None 0.909 11 0 1997 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.909 11 0 2004 2019
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.100 None 1.000 10 0 2000 2020
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.100 None 0.900 10 2 2004 2017
Entrez Id: 23114
Gene Symbol: NFASC
NFASC
O94856 neurofascin 62 0.682 0.423 1.00 0.100 None 1.000 1 1 2013 2013
Entrez Id: 8440
Gene Symbol: NCK2
NCK2
O43639 NCK adaptor protein 2 25 0.743 0.500 0.46 0.100 None 1.000 1 1 2013 2013
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.090 None 0.889 9 5 2004 2020
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
O43612 hypocretin neuropeptide precursor 237 0.500 0.808 2.9E-02 0.090 None 1.000 9 0 2009 2020
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.080 None 1.000 8 1 2004 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.080 None 1.000 8 0 2015 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.070 None 1.000 7 0 2011 2019
Entrez Id: 340075
Gene Symbol: ARSI
ARSI
Q5FYB1 arylsulfatase family member I 55 0.656 0.615 6.0E-15 0.060 None 1.000 6 0 2017 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.060 None 1.000 6 0 2011 2020
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1
Q99720 sigma non-opioid intracellular receptor 1 190 0.544 0.808 0.17 0.060 None 1.000 6 0 2016 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.060 None 0.833 6 0 2016 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.060 None 1.000 6 0 2011 2020
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.060 None 1.000 6 0 2011 2019
Entrez Id: 5308
Gene Symbol: PITX2
PITX2
Q99697 paired like homeodomain 2 248 0.489 0.808 0.98 0.050 None 1.000 5 0 2010 2020
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 590 0.393 0.885 0.97 0.050 None 1.000 5 0 2011 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.050 None 1.000 5 3 2004 2018