Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 1.000 definitive 0.977 608 189 1988 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2003 2003
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 1.000 4 3 2013 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.350 None 1.000 7 1 1999 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 1.000 3 0 1999 2010
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.040 None 1.000 4 1 2012 2015
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2010 2010
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 1996 1996
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.400 None 0.933 15 1 2001 2016
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 2012 2012
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.090 None 0.889 9 0 1999 2019
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
P01562 interferon alpha 1 662 0.371 0.923 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
P01562 interferon alpha 13 646 0.374 0.923 0.010 None 1.000 1 0 2011 2011
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2006 2006
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 10 0 1999 2019
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None < 0.001 1 0 1996 1996
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1
O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.010 None < 0.001 1 0 2004 2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.020 None 1.000 2 0 2016 2018
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
P07900 heat shock protein 90 alpha family class A member 1 Chaperone 455 0.411 0.923 0.86 0.010 None 1.000 1 0 2016 2016