Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 1.000 definitive 0.977 608 189 1988 2020
Entrez Id: 6037
Gene Symbol: RNASE3
RNASE3
P12724 ribonuclease A family member 3 207 0.490 0.808 0.020 None 1.000 2 0 1991 1995
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.020 None 1.000 2 0 1991 1995
Entrez Id: 139818
Gene Symbol: DOCK11
DOCK11
Q5JSL3 dedicator of cytokinesis 11 Enzyme modulator 57 0.606 0.731 1.2E-02 0.010 None 1.000 1 0 1991 1991
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.010 None 1.000 1 0 1994 1994
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.010 None 1.000 1 0 1995 1995
Entrez Id: 4771
Gene Symbol: NF2
NF2
P35240 neurofibromin 2 312 0.468 0.885 1.00 0.010 None 1.000 1 0 1995 1995
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 446 0.422 0.808 1.00 0.010 None 1.000 1 0 1995 1995
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None < 0.001 1 0 1996 1996
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 1996 1996
Entrez Id: 55558
Gene Symbol: PLXNA3
PLXNA3
P51805 plexin A3 42 0.670 0.769 5.5E-02 0.010 None 1.000 1 0 1998 1998
Entrez Id: 7012
Gene Symbol: TERC
TERC
telomerase RNA component 296 0.471 0.846 0.010 None 1.000 1 0 1998 1998
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.700 None 0.963 27 5 1999 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 10 0 1999 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.090 None 0.889 9 0 1999 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.350 None 1.000 7 1 1999 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 1.000 3 0 1999 2010
Entrez Id: 8915
Gene Symbol: BCL10
BCL10
O95999 BCL10 immune signaling adaptor 205 0.491 0.769 0.34 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
P24941 cyclin dependent kinase 2 Kinase 270 0.456 0.692 0.61 0.010 None 1.000 1 0 1999 1999
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.400 None 0.933 15 1 2001 2016
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1
O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.010 None 1.000 1 0 2001 2001
Entrez Id: 57045
Gene Symbol: TWSG1
TWSG1
Q9GZX9 twisted gastrulation BMP signaling modulator 1 57 0.621 0.692 6.1E-03 0.010 None 1.000 1 0 2001 2001
Entrez Id: 6223
Gene Symbol: RPS19
RPS19
P39019 ribosomal protein S19 Nucleic acid binding 256 0.480 0.846 0.92 0.020 None 1.000 2 0 2002 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.010 None 1.000 1 0 2002 2002
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2003 2003