Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11330
Gene Symbol: CTRC
CTRC
Q99895 chymotrypsin C 56 0.653 0.500 1.3E-12 0.010 None 1.000 1 0 2008 2008
Entrez Id: 255239
Gene Symbol: ANKK1
ANKK1
Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 71 0.604 0.462 7.4E-12 0.010 None 1.000 1 0 2013 2013
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.020 None 1.000 2 0 2019 2019
Entrez Id: 3263
Gene Symbol: HPX
HPX
P02790 hemopexin Enzyme 76 0.599 0.731 1.3E-11 0.010 None 1.000 1 0 2019 2019
Entrez Id: 128
Gene Symbol: ADH5
ADH5
P11766 alcohol dehydrogenase 5 (class III), chi polypeptide Enzyme 65 0.604 0.731 2.5E-11 0.200 None 1.000 1 0 1993 1993
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.010 None 1.000 1 1 2016 2016
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 291 0.462 0.885 5.8E-11 0.020 None 1.000 2 0 1999 2018
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.510 None 1.000 3 1 2003 2014
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.600 None 1.000 14 1 1994 2018
Entrez Id: 56938
Gene Symbol: ARNTL2
ARNTL2
Q8WYA1 aryl hydrocarbon receptor nuclear translocator like 2 Transcription factor 41 0.644 0.654 6.0E-10 0.320 None 1.000 2 3 2010 2012
Entrez Id: 26503
Gene Symbol: SLC17A5
SLC17A5
Q9NRA2 solute carrier family 17 member 5 Transporter 252 0.491 0.808 6.9E-10 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.320 None 0.500 4 0 2013 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.740 None 1.000 8 0 1992 2013
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.330 None 1.000 3 0 2011 2015
Entrez Id: 307
Gene Symbol: ANXA4
ANXA4
P09525 annexin A4 74 0.599 0.692 1.2E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7389
Gene Symbol: UROD
UROD
P06132 uroporphyrinogen decarboxylase 166 0.521 0.769 1.3E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 51659
Gene Symbol: GINS2
GINS2
Q9Y248 GINS complex subunit 2 Enzyme 51 0.638 0.577 1.6E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 282617
Gene Symbol: IFNL3
IFNL3
Q8IZI9 interferon lambda 3 175 0.506 0.808 2.4E-08 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.320 None 1.000 3 1 2003 2015
Entrez Id: 134391
Gene Symbol: GPR151
GPR151
Q8TDV0 G protein-coupled receptor 151 G-protein coupled receptor 169 0.530 0.923 3.2E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7018
Gene Symbol: TF
TF
P02787 transferrin Enzyme 168 0.527 0.846 4.1E-08 0.310 None 1.000 3 0 2000 2011
Entrez Id: 165140
Gene Symbol: OXER1
OXER1
Q8TDS5 oxoeicosanoid receptor 1 G-protein coupled receptor 169 0.529 0.923 7.3E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 79068
Gene Symbol: FTO
FTO
Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.010 None 1.000 1 1 2019 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 110 0.588 0.692 1.4E-07 0.300 None 1.000 1 0 2009 2009