Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0 0
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2017 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.100 None 0 0
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.300 None 0 0
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0 0
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
P31645 solute carrier family 6 member 4 Transporter 440 0.429 0.808 0.25 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 0 0
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.100 None 0 0
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.100 None 0 0
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.300 None 1.000 1 0 2002 2002
Entrez Id: 885
Gene Symbol: CCK
CCK
P06307 cholecystokinin 326 0.453 0.846 3.3E-05 0.090 None 1.000 9 0 1993 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
P08729 keratin 7 287 0.463 0.808 3.1E-12 0.020 None 1.000 2 0 2017 2017
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
P21397 monoamine oxidase A 300 0.465 0.769 1.00 0.020 None 1.000 2 0 2004 2016
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 0 0
Entrez Id: 6390
Gene Symbol: SDHB
SDHB
P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.100 None 0 0
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2
P18065 insulin like growth factor binding protein 2 Enzyme modulator 241 0.478 0.769 0.12 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1
P09936 ubiquitin C-terminal hydrolase L1 Enzyme 260 0.482 0.885 0.99 0.100 None 0 0
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
P60880 synaptosome associated protein 25 Transporter 283 0.489 0.808 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2271
Gene Symbol: FH
FH
P07954 fumarate hydratase Enzyme 231 0.489 0.846 8.8E-02 0.100 None 0 0
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
P17542 TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 202 0.505 0.731 0.57 0.020 None 1.000 2 0 2017 2017
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.100 None 0 0