Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.700 0.985 69 32 1991 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 nucleic acid binding; transcription factor 264 0.467 0.828 1.00 0.700 4 2 1990 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.500 0.900 12 2 1985 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.470 1.000 9 1 2002 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 1.000 43 4 1987 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene receptor tyrosine kinase 462 0.394 0.759 0.99 0.400 0.893 28 1 1991 2016
Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
P50553 achaete-scute family bHLH transcription factor 1 nucleic acid binding; transcription factor 111 0.569 0.552 0.70 0.400 1.000 18 0 1997 2018
Entrez Id: 4610
Gene Symbol: MYCL
MYCL
P12524 MYCL proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 55 0.616 0.586 0.12 0.400 1.000 15 0 1988 2012
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 nucleic acid binding 212 0.503 0.759 1.00 0.400 1.000 12 0 2008 2018
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin signaling molecule 238 0.486 0.759 7.5E-02 0.370 1.000 8 0 1988 2004
Entrez Id: 1993
Gene Symbol: ELAVL2
ELAVL2
Q12926 ELAV like RNA binding protein 2 59 0.600 0.621 0.99 0.370 1.000 8 0 1995 2014
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 623 0.388 0.759 1.00 0.360 1.000 7 0 2012 2016
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box 2 transcription factor 251 0.459 0.759 0.73 0.350 1.000 5 0 2000 2016
Entrez Id: 3642
Gene Symbol: INSM1
INSM1
Q01101 INSM transcriptional repressor 1 20 0.752 0.207 0.65 0.340 1.000 5 0 2007 2016
Entrez Id: 9353
Gene Symbol: SLIT2
SLIT2
O94813 slit guidance ligand 2 107 0.550 0.621 1.00 0.310 1.000 2 0 2002 2012
Entrez Id: 1152
Gene Symbol: CKB
CKB
P12277 creatine kinase B kinase; transferase 45 0.636 0.483 0.59 0.310 < 0.001 2 0 1987 1988
Entrez Id: 121256
Gene Symbol: TMEM132D
TMEM132D
Q14C87 transmembrane protein 132D 32 0.659 0.448 1.00 0.310 1.000 2 0 2012 2015
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein nucleic acid binding; transcription factor; transferase 390 0.451 0.862 1.00 0.310 1.000 2 0 2012 2016
Entrez Id: 8570
Gene Symbol: KHSRP
KHSRP
Q92945 KH-type splicing regulatory protein enzyme modulator; hydrolase; nucleic acid binding; protease 60 0.602 0.552 1.00 0.310 1.000 2 0 2012 2017
Entrez Id: 84700
Gene Symbol: MYO18B
MYO18B
Q8IUG5 myosin XVIIIB 51 0.681 0.448 2.6E-30 0.310 1.000 1 0 2002 2002
Entrez Id: 9425
Gene Symbol: CDYL
CDYL
Q9Y232 chromodomain Y like 4 0.857 0.138 0.99 0.300 1 0 2012 2012
Entrez Id: 2899
Gene Symbol: GRIK3
GRIK3
Q13003 glutamate ionotropic receptor kainate type subunit 3 17 0.727 0.379 1.00 0.300 1 0 2012 2012
Entrez Id: 11228
Gene Symbol: RASSF8
RASSF8
Q8NHQ8 Ras association domain family member 8 14 0.752 0.241 0.95 0.300 1 0 2012 2012
Entrez Id: 57683
Gene Symbol: ZDBF2
ZDBF2
Q9HCK1 zinc finger DBF-type containing 2 1 1.000 0.069 1.2E-02 0.300 1 0 2012 2012
Entrez Id: 23314
Gene Symbol: SATB2
SATB2
Q9UPW6 SATB homeobox 2 nucleic acid binding; transcription factor 130 0.588 0.517 1.00 0.300 1 0 2012 2012