Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4397
Gene Symbol: MS
MS
multiple sclerosis 95 0.599 0.692 0.010 None 1.000 1 0 2003 2003
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
Q99062 colony stimulating factor 3 receptor Signaling 120 0.550 0.692 1.5E-10 0.300 None 1.000 1 0 2009 2009
Entrez Id: 4340
Gene Symbol: MOG
MOG
Q16653 myelin oligodendrocyte glycoprotein Enzyme modulator 136 0.546 0.731 0.14 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
P14222 perforin 1 163 0.540 0.692 5.5E-06 0.100 None 0 0
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
O43612 hypocretin neuropeptide precursor 237 0.500 0.808 2.9E-02 0.010 None 1.000 1 0 2020 2020
Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
O43927 C-X-C motif chemokine ligand 13 Signaling 246 0.472 0.731 0.83 0.050 None 1.000 5 0 2018 2019
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related receptor tyrosine kinase 3 Kinase 270 0.462 0.654 0.61 0.300 None 1.000 2 0 2016 2016
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A
O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 320 0.489 0.769 1.00 0.010 None < 0.001 1 0 2003 2003
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 324 0.453 0.923 5.3E-10 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
P05107 integrin subunit beta 2 Receptor 340 0.444 0.923 5.1E-15 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
P11215 integrin subunit alpha M 343 0.443 0.808 3.3E-11 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
P01574 interferon beta 1 426 0.421 0.846 0.010 None < 0.001 1 0 2007 2007
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
P29965 CD40 ligand Signaling 453 0.414 0.846 0.72 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
P13501 C-C motif chemokine ligand 5 Signaling 514 0.403 0.885 1.8E-03 0.020 None 1.000 2 0 2016 2016
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.100 None 0.955 22 0 2017 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.300 None 1.000 1 0 2016 2016
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
P02778 C-X-C motif chemokine ligand 10 Signaling 631 0.378 0.885 0.37 0.010 None 1.000 1 0 2019 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 1 0 2016 2016
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.100 None 0.955 22 0 2017 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.010 None 1.000 1 0 2019 2019