Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.100 None 0.983 59 0 2012 2019
Entrez Id: 27436
Gene Symbol: EML4
EML4
Q9HC35 EMAP like 4 100 0.569 0.577 4.8E-04 0.400 None 0.980 49 0 2009 2019
Entrez Id: 7270
Gene Symbol: TTF1
TTF1
Q15361 transcription termination factor 1 134 0.537 0.500 6.2E-13 0.400 None 1.000 49 0 2009 2020
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 47 0 2001 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.400 None 1.000 33 0 2008 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 33 0 2012 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 33 0 2012 2020
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 0.967 30 0 1994 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.100 None 1.000 26 0 1991 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 26 0 2007 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.923 26 0 2000 2019
Entrez Id: 114131
Gene Symbol: UCN3
UCN3
Q969E3 urocortin 3 82 0.593 0.731 4.4E-02 0.100 None 1.000 23 0 2005 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 21 0 2010 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 20 0 2000 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 18 0 2002 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 17 0 2012 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 17 0 2017 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.400 None 0.882 17 0 2006 2018
Entrez Id: 9476
Gene Symbol: NAPSA
NAPSA
O96009 napsin A aspartic peptidase Enzyme 89 0.576 0.654 7.2E-14 0.100 None 1.000 17 0 1999 2020
Entrez Id: 1287
Gene Symbol: COL4A5
COL4A5
P29400 collagen type IV alpha 5 chain 124 0.553 0.654 1.00 0.100 None 1.000 15 0 2013 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 15 0 2013 2019
Entrez Id: 3799
Gene Symbol: KIF5B
KIF5B
P33176 kinesin family member 5B Cellular structure 67 0.604 0.538 0.99 0.100 None 1.000 15 0 2009 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 15 0 2007 2019
Entrez Id: 81031
Gene Symbol: SLC2A10
SLC2A10
O95528 solute carrier family 2 member 10 Transporter 135 0.550 0.615 1.6E-08 0.100 None 1.000 15 0 2013 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 1.000 14 0 2009 2019