Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.330 None 1.000 1 0 2009 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.700 None 0.967 5 2 1990 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.500 None 1.000 0 10 2001 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.700 None 0.978 2 7 1990 2020
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 123 0.317 0.962 0.64 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.500 None 0.923 1 9 1990 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.700 None 1.000 2 14 2002 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.400 None 1.000 0 0 2008 2020
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 108 0.454 0.731 0.99 0.420 None 0.667 1 0 2015 2017
Entrez Id: 196
Gene Symbol: AHR
AHR 		P35869 aryl hydrocarbon receptor Transcription factor 99 0.410 0.923 1.00 0.400 None 1.000 1 0 1999 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.979 1 19 2010 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.410 None 1.000 0 1 2008 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 93 0.380 0.808 1.00 0.440 None 0.833 0 5 2008 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.500 None 1.000 2 3 2008 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.500 None 0.987 0 6 1989 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.400 None 0.900 0 3 2009 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.400 None 0.882 1 0 2006 2018
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 67 0.390 0.808 0.49 0.420 None 1.000 0 2 2010 2016
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		P09917 arachidonate 5-lipoxygenase Enzyme 64 0.447 0.885 1.2E-06 0.300 None 1.000 1 0 2018 2018
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 59 0.429 0.885 5.5E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 58 0.479 0.808 1.00 0.320 None 1.000 0 0 2011 2019
Entrez Id: 2023
Gene Symbol: ENO1
ENO1 		P06733 enolase 1 Enzyme 57 0.481 0.885 1.9E-05 0.350 None 1.000 2 0 2010 2019
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 56 0.362 0.769 1.00 0.500 None 0.929 1 5 2010 2017
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 53 0.378 0.885 1.00 0.360 None 1.000 0 0 2001 2019
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 49 0.413 0.885 0.13 0.320 None 1.000 1 0 2007 2014