Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.610 None 1.000 1 1 2000 2000
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.500 None 1.000 43 1 1988 2019
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.500 None 0 1
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase Enzyme 356 0.453 0.808 1.2E-15 0.410 None 1.000 1 0 2019 2019
Entrez Id: 6049
Gene Symbol: RNF6
RNF6
Q9Y252 ring finger protein 6 46 0.656 0.615 1.4E-02 0.400 None 0 0
Entrez Id: 49860
Gene Symbol: CRNN
CRNN
Q9UBG3 cornulin Calcium-binding protein 22 0.736 0.308 1.3E-04 0.320 None 1.000 3 1 2000 2014
Entrez Id: 11178
Gene Symbol: LZTS1
LZTS1
Q9Y250 leucine zipper tumor suppressor 1 50 0.633 0.385 0.95 0.300 None 0 0
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 0.985 134 77 1990 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.200 None 1.000 31 1 1993 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.200 None 0.957 23 1 1994 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.200 None 0.952 21 8 2006 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.200 None 1.000 17 4 2002 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.170 None 1.000 8 1 1992 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.160 None 1.000 6 2 1996 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.150 None 0.833 6 3 1994 2017
Entrez Id: 79651
Gene Symbol: RHBDF2
RHBDF2
Q6PJF5 rhomboid 5 homolog 2 Enzyme 90 0.595 0.538 1.2E-03 0.150 None 1.000 5 0 1998 2012
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.130 None 1.000 4 3 1992 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.130 None 1.000 4 4 1996 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 257 0.465 0.808 1.00 0.120 None 1.000 3 4 2012 2018
Entrez Id: 100270680
Gene Symbol: CASC11
CASC11
cancer susceptibility 11 45 0.641 0.577 0.110 None 1.000 2 3 2016 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.110 None 1.000 2 3 2009 2016
Entrez Id: 6772
Gene Symbol: STAT1
STAT1
P42224 signal transducer and activator of transcription 1 Nucleic acid binding 531 0.399 0.885 1.00 0.110 None 1.000 1 0 2019 2019
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
P05091 aldehyde dehydrogenase 2 family member Enzyme 337 0.457 0.885 3.4E-10 0.100 None 0.981 54 2 1996 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 0.969 32 0 2017 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.964 28 0 1993 2019