Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2057
Gene Symbol: EPOR
EPOR
P19235 erythropoietin receptor receptor 115 0.555 0.552 7.1E-03 0.700 strong 0.846 18 1 1993 2015
Entrez Id: 54583
Gene Symbol: EGLN1
EGLN1
Q9GZT9 egl-9 family hypoxia inducible factor 1 65 0.594 0.552 0.98 0.380 strong 0.875 12 1 2006 2017
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
Q99814 endothelial PAS domain protein 1 nucleic acid binding; transcription factor 153 0.509 0.586 0.50 0.350 strong 1.000 10 1 2008 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 373 0.430 0.690 0.47 0.330 0.667 3 2 2007 2017
Entrez Id: 3043
Gene Symbol: HBB
HBB
P68871 hemoglobin subunit beta 196 0.513 0.793 1.4E-08 0.310 strong 1.000 8 0 2005 2017
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor 293 0.464 0.586 5.5E-02 0.310 strong 1.000 8 0 2003 2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.310 limited 1.000 2 0 2008 2012
Entrez Id: 3040
Gene Symbol: HBA2
HBA2
P69905 hemoglobin subunit alpha 2 158 0.524 0.724 3.1E-03 0.300 strong 9 0 1990 2017
Entrez Id: 3039
Gene Symbol: HBA1
HBA1
P69905 hemoglobin subunit alpha 1 183 0.508 0.759 6.3E-03 0.300 strong 7 0 2005 2017
Entrez Id: 669
Gene Symbol: BPGM
BPGM
P07738 bisphosphoglycerate mutase 10 0.815 0.138 2.3E-02 0.300 strong 5 0 1969 2017
Entrez Id: 112398
Gene Symbol: EGLN2
EGLN2
Q96KS0 egl-9 family hypoxia inducible factor 2 46 0.624 0.586 0.74 0.300 limited 1 0 2012 2012
Entrez Id: 5313
Gene Symbol: PKLR
PKLR
P30613 pyruvate kinase L/R 131 0.537 0.759 4.8E-07 0.300 limited 1 0 2012 2012
Entrez Id: 112399
Gene Symbol: EGLN3
EGLN3
Q9H6Z9 egl-9 family hypoxia inducible factor 3 63 0.596 0.552 1.0E-02 0.300 limited 1 0 2012 2012
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
Q9UQQ2 SH2B adaptor protein 3 135 0.575 0.552 6.7E-05 0.300 0 0
Entrez Id: 2056
Gene Symbol: EPO
EPO
P01588 erythropoietin 360 0.425 0.759 1.2E-02 0.100 1.000 10 0 1982 2018
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B
P51692 signal transducer and activator of transcription 5B nucleic acid binding; transcription factor 178 0.490 0.690 1.00 0.010 1.000 1 0 1999 1999
Entrez Id: 54776
Gene Symbol: PPP1R12C
PPP1R12C
Q9BZL4 protein phosphatase 1 regulatory subunit 12C 23 0.707 0.414 0.75 0.010 1.000 1 0 2009 2009
Entrez Id: 4352
Gene Symbol: MPL
MPL
P40238 MPL proto-oncogene, thrombopoietin receptor receptor 145 0.554 0.655 3.3E-09 0.010 1.000 1 0 2008 2008
Entrez Id: 23368
Gene Symbol: PPP1R13B
PPP1R13B
Q96KQ4 protein phosphatase 1 regulatory subunit 13B enzyme modulator 32 0.667 0.448 1.00 0.010 1.000 1 0 2009 2009
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A nucleic acid binding; transcription factor 184 0.489 0.759 1.00 0.010 1.000 1 0 1999 1999
Entrez Id: 9139
Gene Symbol: CBFA2T2
CBFA2T2
O43439 CBFA2/RUNX1 translocation partner 2 transcription factor 33 0.681 0.448 1.00 0.010 1.000 1 0 2009 2009
Entrez Id: 8874
Gene Symbol: ARHGEF7
ARHGEF7
Q14155 Rho guanine nucleotide exchange factor 7 116 0.533 0.724 1.00 0.010 1.000 1 0 2009 2009
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
P27986 phosphoinositide-3-kinase regulatory subunit 1 enzyme modulator 219 0.515 0.793 1.00 0.010 1.000 1 0 2009 2009
Entrez Id: 5296
Gene Symbol: PIK3R2
PIK3R2
O00459 phosphoinositide-3-kinase regulatory subunit 2 enzyme modulator 97 0.594 0.655 1.3E-02 0.010 1.000 1 0 2009 2009