Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 10 3 2011 2019
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		P02458 collagen type II alpha 1 chain 496 0.444 0.846 1.00 0.050 None 1.000 5 3 2016 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.875 24 2 1998 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.030 None 1.000 3 2 2010 2014
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.010 None 1.000 1 2 2013 2013
Entrez Id: 356
Gene Symbol: FASLG
FASLG 		P48023 Fas ligand Signaling 398 0.430 0.885 0.18 0.010 None 1.000 1 2 2013 2013
Entrez Id: 8200
Gene Symbol: GDF5
GDF5 		P43026 growth differentiation factor 5 Signaling 238 0.511 0.692 0.67 0.050 None 1.000 5 1 2004 2019
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.330 strong 1.000 4 1 2010 2017
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.040 None 0.750 4 1 2013 2019
Entrez Id: 8483
Gene Symbol: CILP
CILP 		O75339 cartilage intermediate layer protein 19 0.736 0.423 5.4E-26 0.040 None 1.000 4 1 2005 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.030 None 1.000 3 1 2009 2017
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.030 None 1.000 3 1 2013 2014
Entrez Id: 79068
Gene Symbol: FTO
FTO 		Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.030 None 1.000 3 1 2013 2018
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1 		P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.020 None 1.000 2 1 2016 2017
Entrez Id: 2735
Gene Symbol: GLI1
GLI1 		P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.010 None 1.000 1 1 2013 2013
Entrez Id: 3489
Gene Symbol: IGFBP6
IGFBP6 		P24592 insulin like growth factor binding protein 6 Enzyme modulator 71 0.601 0.692 2.9E-02 0.010 None 1.000 1 1 2017 2017
Entrez Id: 10082
Gene Symbol: GPC6
GPC6 		Q9Y625 glypican 6 86 0.626 0.654 0.14 0.100 None 1.000 1 1 2013 2013
Entrez Id: 56243
Gene Symbol: KIAA1217
KIAA1217 		Q5T5P2 KIAA1217 19 0.769 0.308 2.3E-04 0.010 None 1.000 1 1 2011 2011
Entrez Id: 64478
Gene Symbol: CSMD1
CSMD1 		Q96PZ7 CUB and Sushi multiple domains 1 90 0.610 0.500 1.00 0.100 None 1.000 1 1 2013 2013
Entrez Id: 4148
Gene Symbol: MATN3
MATN3 		O15232 matrilin 3 Receptor 79 0.644 0.385 1.4E-08 0.010 None 1.000 1 1 2006 2006
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 1.000 1 1 2013 2013
Entrez Id: 6687
Gene Symbol: SPG7
SPG7 		Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 419 0.436 0.885 2.0E-36 0.100 None 0 1
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 31 0 2004 2019
Entrez Id: 176
Gene Symbol: ACAN
ACAN 		P16112 aggrecan Extracellular structure 187 0.528 0.846 1.00 0.100 None 0.962 26 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 24 0 2013 2019