Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3081
Gene Symbol: HGD
HGD
Q93099 homogentisate 1,2-dioxygenase Enzyme 70 0.631 0.577 3.0E-08 0.100 None 0 0
Entrez Id: 6687
Gene Symbol: SPG7
SPG7
Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 419 0.436 0.885 2.0E-36 0.100 None 0 1
Entrez Id: 4161
Gene Symbol: MC5R
MC5R
P33032 melanocortin 5 receptor G-protein coupled receptor 16 0.743 0.423 6.5E-05 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 406948
Gene Symbol: MIR15A
MIR15A
microRNA 15a 221 0.482 0.808 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
Q04656 ATPase copper transporting alpha Transporter 348 0.494 0.769 1.00 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 972
Gene Symbol: CD74
CD74
P04233 CD74 molecule Enzyme modulator 170 0.512 0.808 0.25 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 4159
Gene Symbol: MC3R
MC3R
P41968 melanocortin 3 receptor G-protein coupled receptor 33 0.695 0.462 1.0E-07 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 728638
Gene Symbol: KRT8P3
KRT8P3
keratin 8 pseudogene 3 50 0.644 0.538 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
P05787 keratin 8 166 0.517 0.654 2.4E-08 0.020 None 0.500 2 0 2013 2015
Entrez Id: 1298
Gene Symbol: COL9A2
COL9A2
Q14055 collagen type IX alpha 2 chain 116 0.572 0.769 1.0E-08 0.040 None 0.750 4 0 2003 2015
Entrez Id: 5903
Gene Symbol: RANBP2
RANBP2
P49792 RAN binding protein 2 Enzyme modulator 110 0.578 0.615 1.00 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3
Q13507 transient receptor potential cation channel subfamily C member 3 Ion channel 102 0.570 0.731 1.1E-07 0.040 None 0.750 4 0 2002 2018
Entrez Id: 1638
Gene Symbol: DCT
DCT
P40126 dopachrome tautomerase Enzyme 59 0.619 0.654 7.4E-14 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7218
Gene Symbol: TRP-AGG2-6
TRP-AGG2-6
tRNA-Pro (anticodon AGG) 2-6 34 0.666 0.462 0.040 None 0.750 4 0 2005 2015
Entrez Id: 7219
Gene Symbol: TRP-TGG3-1
TRP-TGG3-1
tRNA-Pro (anticodon TGG) 3-1 11 0.780 0.269 0.040 None 0.750 4 0 2002 2018
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.040 None 0.750 4 1 2013 2019
Entrez Id: 1299
Gene Symbol: COL9A3
COL9A3
Q14050 collagen type IX alpha 3 chain 125 0.569 0.769 3.3E-12 0.060 None 0.833 6 0 2002 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.875 24 2 1998 2020
Entrez Id: 176
Gene Symbol: ACAN
ACAN
P16112 aggrecan Extracellular structure 187 0.528 0.846 1.00 0.100 None 0.962 26 0 2002 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 31 0 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 24 0 2013 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 10 3 2011 2019
Entrez Id: 655
Gene Symbol: BMP7
BMP7
P18075 bone morphogenetic protein 7 Signaling 197 0.498 0.769 0.13 0.090 None 1.000 9 0 2016 2019