Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 31 0 2004 2019
Entrez Id: 176
Gene Symbol: ACAN
ACAN
P16112 aggrecan Extracellular structure 187 0.528 0.846 1.00 0.100 None 0.962 26 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 24 0 2013 2019
Entrez Id: 655
Gene Symbol: BMP7
BMP7
P18075 bone morphogenetic protein 7 Signaling 197 0.498 0.769 0.13 0.090 None 1.000 9 0 2016 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.080 None 1.000 8 0 2004 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.360 None 1.000 7 0 2005 2020
Entrez Id: 1299
Gene Symbol: COL9A3
COL9A3
Q14050 collagen type IX alpha 3 chain 125 0.569 0.769 3.3E-12 0.060 None 0.833 6 0 2002 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.060 None 1.000 6 0 2014 2018
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.060 None 1.000 6 0 2002 2018
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.050 None 1.000 5 0 2003 2019
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.050 None 1.000 5 0 2017 2019
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4
O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 84 0.582 0.692 2.0E-06 0.050 None 1.000 5 0 2006 2019
Entrez Id: 650
Gene Symbol: BMP2
BMP2
P12643 bone morphogenetic protein 2 Signaling 428 0.432 0.846 0.99 0.040 None 1.000 4 0 2007 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.040 None 1.000 4 0 2005 2019
Entrez Id: 1298
Gene Symbol: COL9A2
COL9A2
Q14055 collagen type IX alpha 2 chain 116 0.572 0.769 1.0E-08 0.040 None 0.750 4 0 2003 2015
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.040 None 1.000 4 0 2003 2015
Entrez Id: 7218
Gene Symbol: TRP-AGG2-6
TRP-AGG2-6
tRNA-Pro (anticodon AGG) 2-6 34 0.666 0.462 0.040 None 0.750 4 0 2005 2015
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.040 None 1.000 4 0 2013 2019
Entrez Id: 7219
Gene Symbol: TRP-TGG3-1
TRP-TGG3-1
tRNA-Pro (anticodon TGG) 3-1 11 0.780 0.269 0.040 None 0.750 4 0 2002 2018
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.040 None 1.000 4 0 2008 2017
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
microRNA 155 584 0.384 0.885 0.040 None 1.000 4 0 2011 2019
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3
Q13507 transient receptor potential cation channel subfamily C member 3 Ion channel 102 0.570 0.731 1.1E-07 0.040 None 0.750 4 0 2002 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.040 None 1.000 4 0 2016 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.040 None 1.000 4 0 2017 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.040 None 1.000 4 0 2016 2019