Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 1999 1999
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 0 2006 2006
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.020 None 1.000 2 0 2015 2019
Entrez Id: 3342
Gene Symbol: HTC2
HTC2 		hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.020 None 0.500 2 0 2013 2017
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		P51608 methyl-CpG binding protein 2 Epigenetic regulator 664 0.414 0.846 0.89 0.500 strong 0.917 12 9 2001 2014
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		Q92793 CREB binding protein 438 0.428 0.808 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 1.000 10 0 2004 2019
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		Q9UKV0 histone deacetylase 9 Epigenetic regulator 340 0.439 0.846 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		F7VJQ1 P04156 prion protein 426 0.445 0.923 6.3E-04 0.040 None 1.000 4 0 1998 2012
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3 		Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2033
Gene Symbol: EP300
EP300 		Q09472 E1A binding protein p300 345 0.459 0.846 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3065
Gene Symbol: HDAC1
HDAC1 		Q13547 histone deacetylase 1 Epigenetic regulator 277 0.460 0.846 0.61 0.020 None 1.000 2 0 2017 2019
Entrez Id: 6925
Gene Symbol: TCF4
TCF4 		P15884 transcription factor 4 Transcription factor 378 0.464 0.846 1.00 0.030 None 1.000 3 0 2010 2014
Entrez Id: 4485
Gene Symbol: MST1
MST1 		P26927 macrophage stimulating 1 Enzyme 281 0.465 0.885 4.8E-19 0.010 None 1.000 1 0 2012 2012
Entrez Id: 79594
Gene Symbol: MUL1
MUL1 		Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.100 None 1.000 10 0 2004 2019
Entrez Id: 2332
Gene Symbol: FMR1
FMR1 		Q06787 FMRP translational regulator 1 Nucleic acid binding 346 0.473 0.769 0.65 0.010 None 1.000 1 0 2017 2017
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2 		Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.100 None 1.000 10 0 2004 2019
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2 		Q92769 histone deacetylase 2 Epigenetic regulator 257 0.476 0.846 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4477
Gene Symbol: MSMB
MSMB 		P08118 microseminoprotein beta Signaling 195 0.498 0.846 1.6E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1 		P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 219 0.504 0.769 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6 		Q92581 solute carrier family 9 member A6 Transporter 210 0.516 0.846 1.00 0.050 None 1.000 5 0 2008 2014