Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2245
Gene Symbol: FGD1
FGD1 		P98174 FYVE, RhoGEF and PH domain containing 1 Enzyme modulator 131 0.573 0.731 1.00 0.800 definitive 0.935 31 12 1994 2017
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.230 None 1.000 4 0 2000 2017
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.200 None 1.000 2 0 2011 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 1 0 2014 2014
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.200 None 1.000 1 0 2019 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.200 None 1.000 1 0 2004 2004
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.200 None 1.000 1 0 2018 2018
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.200 None 0 0
Entrez Id: 80254
Gene Symbol: CEP63
CEP63 		Q96MT8 centrosomal protein 63 Cellular structure 44 0.666 0.500 6.2E-25 0.200 None 0 0
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.200 None 0 0
Entrez Id: 4158
Gene Symbol: MC2R
MC2R 		Q01718 melanocortin 2 receptor G-protein coupled receptor 109 0.582 0.654 3.1E-04 0.100 None 0.935 31 4 1994 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC 		P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.100 None 1.000 21 4 1994 2019
Entrez Id: 90121
Gene Symbol: TSR2
TSR2 		Q969E8 TSR2 ribosome maturation factor 31 0.743 0.500 0.80 0.100 None 0 1
Entrez Id: 56246
Gene Symbol: MRAP
MRAP 		Q8TCY5 melanocortin 2 receptor accessory protein 51 0.674 0.500 2.1E-03 0.080 None 1.000 8 0 2006 2019
Entrez Id: 23530
Gene Symbol: NNT
NNT 		Q13423 nicotinamide nucleotide transhydrogenase Enzyme 88 0.601 0.577 0.97 0.060 None 1.000 6 1 2013 2016
Entrez Id: 6770
Gene Symbol: STAR
STAR 		P49675 steroidogenic acute regulatory protein 177 0.513 0.808 8.8E-11 0.060 None 0.833 6 3 2009 2019
Entrez Id: 10587
Gene Symbol: TXNRD2
TXNRD2 		Q9NNW7 thioredoxin reductase 2 Enzyme 134 0.548 0.731 3.5E-11 0.040 None 0.750 4 0 2014 2019
Entrez Id: 9181
Gene Symbol: ARHGEF2
ARHGEF2 		Q92974 Rho/Rac guanine nucleotide exchange factor 2 205 0.502 0.769 1.00 0.030 None 1.000 3 0 2000 2010
Entrez Id: 5923
Gene Symbol: RASGRF1
RASGRF1 		Q13972 Ras protein specific guanine nucleotide releasing factor 1 Enzyme modulator 124 0.537 0.769 1.00 0.030 None 1.000 3 0 2000 2017
Entrez Id: 56731
Gene Symbol: SLC2A4RG
SLC2A4RG 		Q9NR83 SLC2A4 regulator Transcription factor 66 0.615 0.692 0.22 0.030 None 1.000 3 0 2000 2010
Entrez Id: 152273
Gene Symbol: FGD5
FGD5 		Q6ZNL6 FYVE, RhoGEF and PH domain containing 5 Enzyme modulator 24 0.780 0.346 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 1583
Gene Symbol: CYP11A1
CYP11A1 		P05108 cytochrome P450 family 11 subfamily A member 1 166 0.547 0.731 5.5E-07 0.020 None 0.500 2 0 2015 2019
Entrez Id: 8879
Gene Symbol: SGPL1
SGPL1 		O95470 sphingosine-1-phosphate lyase 1 85 0.597 0.731 3.6E-03 0.020 None 0.500 2 0 2017 2019
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		P10071 GLI family zinc finger 3 400 0.436 0.846 1.00 0.020 None 0.500 2 0 1991 1997
Entrez Id: 4173
Gene Symbol: MCM4
MCM4 		P33991 minichromosome maintenance complex component 4 Enzyme 43 0.666 0.654 1.5E-04 0.020 None 1.000 2 0 2013 2013