Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 1.000 5 0 1994 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.300 None 1.000 5 0 1989 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.310 None 1.000 4 0 1999 2010
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.300 None 1.000 3 0 2000 2005
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.030 None 1.000 3 0 2006 2017
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.030 None 1.000 3 0 2006 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.300 None 1.000 2 0 2010 2011
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A
P42229 signal transducer and activator of transcription 5A Nucleic acid binding 318 0.445 0.808 1.00 0.300 None 1.000 2 0 2010 2011
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.020 None 1.000 2 0 2018 2019
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
Q13228 selenium binding protein 1 Immune response 214 0.493 0.846 3.2E-16 0.300 None 1.000 2 0 2004 2004
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 None 1.000 2 0 2010 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.300 None 1.000 2 0 1992 2009
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.300 None 1.000 2 0 2011 2011
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.300 None 1.000 2 0 2005 2011
Entrez Id: 2158
Gene Symbol: F9
F9
P00740 coagulation factor IX Enzyme 276 0.465 0.885 1.00 0.020 None 1.000 2 0 2014 2017
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.300 None 1.000 2 0 1997 2005
Entrez Id: 5726
Gene Symbol: TAS2R38
TAS2R38
P59533 taste 2 receptor member 38 G-protein coupled receptor 149 0.531 0.808 0.13 0.020 None 1.000 2 0 2014 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.300 None 1.000 2 0 2009 2015
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.310 None 1.000 2 0 2000 2010
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.310 None 1.000 2 0 2002 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 2 0 1999 2006
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
Q16204 coiled-coil domain containing 6 156 0.517 0.808 0.58 0.020 None 1.000 2 0 2014 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.300 None 1.000 1 0 2015 2015
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
P16473 thyroid stimulating hormone receptor G-protein coupled receptor 250 0.486 0.808 3.0E-15 0.010 None 1.000 1 0 1999 1999
Entrez Id: 59340
Gene Symbol: HRH4
HRH4
Q9H3N8 histamine receptor H4 G-protein coupled receptor 48 0.659 0.462 5.2E-08 0.300 None 1.000 1 0 2012 2012