Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 1 1 2019 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 1.000 2 1 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 1 2 2019 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 1.000 1 1 2019 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.100 None 1.000 1 1 2019 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.100 None 1.000 2 2 2019 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.100 None 1.000 2 2 2018 2019
Entrez Id: 947
Gene Symbol: CD34
CD34
P28906 CD34 molecule 674 0.368 0.808 5.0E-06 0.100 None 1.000 1 1 2019 2019
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.100 None 1.000 1 1 2019 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.100 None 1.000 1 1 2019 2019
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4
P34932 heat shock protein family A (Hsp70) member 4 550 0.394 0.923 1.00 0.100 None 1.000 2 1 2018 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.100 None 1.000 1 1 2019 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.100 None 1.000 3 2 2018 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.100 None 1.000 1 1 2019 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.100 None 1.000 1 3 2019 2019
Entrez Id: 65125
Gene Symbol: WNK1
WNK1
Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 460 0.416 0.846 1.00 0.100 None 1.000 1 1 2019 2019
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.100 None 1.000 2 3 2019 2019
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.100 None 1.000 1 1 2019 2019
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 446 0.422 0.808 1.00 0.100 None 1.000 1 1 2019 2019
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
P13591 neural cell adhesion molecule 1 445 0.415 0.885 1.00 0.100 None 1.000 2 2 2018 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.100 None 1.000 1 1 2013 2013
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
P10321 major histocompatibility complex, class I, C 435 0.415 0.846 1.6E-06 0.100 None 1.000 1 1 2019 2019
Entrez Id: 650
Gene Symbol: BMP2
BMP2
P12643 bone morphogenetic protein 2 Signaling 428 0.432 0.846 0.99 0.100 None 1.000 1 1 2019 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.100 None 1.000 1 1 2019 2019
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 404 0.425 0.846 0.79 0.100 None 1.000 1 1 2019 2019