Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.210 None 1.000 2 0 2004 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 1 0 2010 2010
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.310 None 0.500 2 2 2013 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.300 None 1.000 1 0 2013 2013
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.300 None 1.000 1 0 2014 2014
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.310 None 1.000 2 0 2004 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.090 None 1.000 9 0 2010 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.300 None 1.000 1 0 2014 2014
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.300 None 1.000 1 0 2013 2013
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 726 0.363 0.846 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 693 0.369 0.885 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3082
Gene Symbol: HGF
HGF 		P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.310 None 1.000 2 0 2001 2011
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 None 1.000 1 0 2001 2001
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.300 None 1.000 1 0 2013 2013
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.300 None 1.000 1 0 2014 2014
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.300 None 1.000 1 0 2010 2010
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.130 None 1.000 3 0 2005 2014
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.150 None 1.000 5 0 2010 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.300 None 1.000 2 0 2010 2013
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2 		Q04721 notch receptor 2 384 0.441 0.808 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 546
Gene Symbol: ATRX
ATRX 		P46100 ATRX chromatin remodeler 412 0.452 0.808 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1 		P43699 NK2 homeobox 1 Transcription factor 319 0.457 0.808 0.36 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 284 0.479 0.808 1.00 0.300 None 1.000 1 0 2013 2013