Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.330 None 1.000 4 0 1994 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.300 None 1.000 1 0 1998 1998
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
Q01844 EWS RNA binding protein 1 Nucleic acid binding 251 0.474 0.692 1.00 0.100 None 1.000 10 0 2011 2018
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.060 None 1.000 6 0 2011 2017
Entrez Id: 9476
Gene Symbol: NAPSA
NAPSA
O96009 napsin A aspartic peptidase Enzyme 89 0.576 0.654 7.2E-14 0.060 None 1.000 6 0 2013 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.040 None 0.500 4 0 2001 2014
Entrez Id: 466
Gene Symbol: ATF1
ATF1
P18846 activating transcription factor 1 88 0.588 0.577 0.63 0.040 None 1.000 4 0 2011 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.030 None 1.000 3 0 2009 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 1.000 3 0 2000 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2013 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.020 None 1.000 2 0 2011 2012
Entrez Id: 53340
Gene Symbol: SPA17
SPA17
Q15506 sperm autoantigenic protein 17 48 0.647 0.577 6.6E-03 0.020 None 1.000 2 0 2007 2018
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 270 0.460 0.846 0.95 0.020 None 1.000 2 0 2013 2015
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B Nucleic acid binding 279 0.473 0.808 1.00 0.020 None 1.000 2 0 2013 2019
Entrez Id: 2719
Gene Symbol: GPC3
GPC3
P51654 glypican 3 311 0.466 0.808 1.00 0.020 None 1.000 2 0 2010 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.020 None 1.000 2 0 1997 2016
Entrez Id: 201163
Gene Symbol: FLCN
FLCN
Q8NFG4 folliculin 160 0.537 0.885 0.79 0.020 None 1.000 2 1 2009 2013
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
P16220 cAMP responsive element binding protein 1 294 0.463 0.885 1.00 0.020 None 1.000 2 0 2012 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.020 None 1.000 2 0 2003 2005
Entrez Id: 84692
Gene Symbol: CCDC54
CCDC54
Q8NEL0 coiled-coil domain containing 54 43 0.659 0.500 1.1E-10 0.020 None 1.000 2 0 2007 2018
Entrez Id: 57876
Gene Symbol: MUC3B
MUC3B
Q9H195 mucin 3B, cell surface associated 41 0.666 0.462 0.010 None 1.000 1 0 2002 2002
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.010 None 1.000 1 0 2007 2007
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 Kinase 144 0.535 0.731 0.33 0.010 None 1.000 1 0 1996 1996
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
P24864 cyclin E1 Enzyme modulator 133 0.538 0.731 0.97 0.010 None 1.000 1 0 2017 2017