Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.020 None 1.000 2 0 2011 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 1999 2010
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.020 None 1.000 2 0 2018 2019
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
P33527 ATP binding cassette subfamily C member 1 Transporter 333 0.445 0.808 1.2E-03 0.020 None 1.000 2 0 2002 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2002 2003
Entrez Id: 5529
Gene Symbol: PPP2R5E
PPP2R5E
Q16537 protein phosphatase 2 regulatory subunit B'epsilon Enzyme 33 0.691 0.423 1.00 0.020 None 1.000 2 0 2009 2010
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
P20585 mutS homolog 3 Nucleic acid binding 245 0.474 0.769 7.4E-31 0.020 None 1.000 2 0 2002 2014
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.020 None 1.000 2 0 2017 2019
Entrez Id: 466
Gene Symbol: ATF1
ATF1
P18846 activating transcription factor 1 88 0.588 0.577 0.63 0.020 None 1.000 2 0 2003 2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.020 None 1.000 2 0 2012 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.020 None 1.000 2 0 2015 2016
Entrez Id: 1718
Gene Symbol: DHCR24
DHCR24
Q15392 24-dehydrocholesterol reductase Enzyme 216 0.498 0.769 3.1E-02 0.020 None 1.000 2 0 2017 2020
Entrez Id: 6271
Gene Symbol: S100A1
S100A1
P23297 S100 calcium binding protein A1 Calcium-binding protein 396 0.421 0.846 6.0E-03 0.020 None 1.000 2 0 2018 2018
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.020 None 1.000 2 0 2007 2012
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.020 None 1.000 2 0 2013 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2014 2017
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.020 None 1.000 2 0 2018 2018
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.020 None 1.000 2 0 1998 2017
Entrez Id: 2152
Gene Symbol: F3
F3
P13726 coagulation factor III, tissue factor Receptor 456 0.415 0.846 1.9E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.020 None 1.000 2 0 2006 2019
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
P22455 fibroblast growth factor receptor 4 Kinase 220 0.490 0.769 7.2E-13 0.020 None 1.000 2 0 2003 2007
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
Q12778 forkhead box O1 380 0.433 0.846 1.00 0.020 None 1.000 2 0 2011 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.020 None 1.000 2 0 2010 2017
Entrez Id: 64764
Gene Symbol: CREB3L2
CREB3L2
Q70SY1 cAMP responsive element binding protein 3 like 2 35 0.691 0.115 1.5E-03 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
P08575 protein tyrosine phosphatase receptor type C Enzyme 366 0.435 0.808 1.00 0.010 None 1.000 1 0 2017 2017