Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2201
Gene Symbol: FBN2
FBN2
P35556 fibrillin 2 Calcium-binding protein 211 0.505 0.808 1.00 1.000 strong 0.979 47 28 1973 2019
Entrez Id: 7136
Gene Symbol: TNNI2
TNNI2
P48788 troponin I2, fast skeletal type Cellular structure 64 0.631 0.423 0.14 0.200 None 1.000 1 0 2014 2014
Entrez Id: 9427
Gene Symbol: ECEL1
ECEL1
O95672 endothelin converting enzyme like 1 Enzyme 60 0.638 0.308 4.8E-13 0.200 None 0 0
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.170 None 1.000 7 1 1993 2012
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 1.000 12 0 2012 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 2009 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.100 None 1.000 11 0 2011 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 1.000 10 0 2011 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 10 1 2008 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.090 None 1.000 9 0 2008 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.090 None 1.000 9 0 2008 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.090 None 1.000 9 1 2008 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.070 None 0.857 7 0 2010 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.070 None 1.000 7 0 2010 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.060 None 1.000 6 0 2017 2020
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.060 None 0.833 6 0 2014 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.060 None 0.833 6 1 2013 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.060 None 1.000 6 0 2011 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 0.800 5 0 2013 2015
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.050 None 1.000 5 0 2016 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.050 None 1.000 5 0 2009 2019
Entrez Id: 8841
Gene Symbol: HDAC3
HDAC3
O15379 histone deacetylase 3 Epigenetic regulator 179 0.511 0.731 0.57 0.050 None 1.000 5 0 2016 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.050 None 1.000 5 0 2015 2018
Entrez Id: 885
Gene Symbol: CCK
CCK
P06307 cholecystokinin 326 0.453 0.846 3.3E-05 0.040 None 1.000 4 0 2017 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.040 None 0.750 4 0 2013 2017