Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.700 None 0.978 274 45 1978 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 349 0.456 0.885 0.100 None 1.000 22 0 2000 2019
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
P08246 elastase, neutrophil expressed Enzyme 346 0.447 0.846 1.2E-03 0.100 None 0.923 13 0 1981 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.030 None 1.000 3 0 1997 2012
Entrez Id: 2006
Gene Symbol: ELN
ELN
P15502 elastin 545 0.415 0.885 2.1E-14 0.030 None 1.000 3 0 2003 2019
Entrez Id: 388007
Gene Symbol: SERPINA13P
SERPINA13P
Q6UXR4 serpin family A member 13, pseudogene 59 0.619 0.692 0.030 None 1.000 3 0 1995 2005
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.030 None 1.000 3 1 2005 2017
Entrez Id: 12
Gene Symbol: SERPINA3
SERPINA3
P01011 serpin family A member 3 Enzyme modulator 229 0.486 0.846 8.8E-14 0.030 None 0.667 3 0 1985 1990
Entrez Id: 710
Gene Symbol: SERPING1
SERPING1
P05155 serpin family G member 1 Enzyme modulator 207 0.507 0.769 0.96 0.020 None 1.000 2 0 2003 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2007 2008
Entrez Id: 146
Gene Symbol: ADRA1D
ADRA1D
P25100 adrenoceptor alpha 1D G-protein coupled receptor 48 0.636 0.731 4.0E-05 0.020 None 1.000 2 0 2017 2018
Entrez Id: 2
Gene Symbol: A2M
A2M
P01023 alpha-2-macroglobulin Enzyme modulator 147 0.529 0.769 4.5E-11 0.020 None 0.500 2 0 1981 1983
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.020 None 1.000 2 0 2015 2017
Entrez Id: 5292
Gene Symbol: PIM1
PIM1
P11309 Pim-1 proto-oncogene, serine/threonine kinase Kinase 224 0.482 0.769 0.85 0.010 None 1.000 1 0 1987 1987
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 56886
Gene Symbol: UGGT1
UGGT1
Q9NYU2 UDP-glucose glycoprotein glucosyltransferase 1 Enzyme 32 0.682 0.385 5.2E-10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
P24158 proteinase 3 Enzyme 215 0.503 0.808 3.8E-05 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5626
Gene Symbol: PROP1
PROP1
O75360 PROP paired-like homeobox 1 117 0.576 0.615 8.8E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 51643
Gene Symbol: TMBIM4
TMBIM4
Q9HC24 transmembrane BAX inhibitor motif containing 4 21 0.743 0.500 3.9E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 53342
Gene Symbol: IL17D
IL17D
Q8TAD2 interleukin 17D 259 0.464 0.808 0.20 0.010 None 1.000 1 0 2019 2019
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
P35670 ATPase copper transporting beta Transporter 182 0.529 0.654 4.8E-30 0.010 None 1.000 1 0 2019 2019
Entrez Id: 56005
Gene Symbol: MYDGF
MYDGF
Q969H8 myeloid derived growth factor 295 0.451 0.846 3.5E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 54738
Gene Symbol: FEV
FEV
Q99581 FEV transcription factor, ETS family member Transcription factor 86 0.593 0.692 8.1E-03 0.010 None 1.000 1 0 2005 2005
Entrez Id: 55829
Gene Symbol: SELENOS
SELENOS
Q9BQE4 selenoprotein S 55 0.628 0.615 1.4E-09 0.010 None 1.000 1 0 2013 2013
Entrez Id: 51726
Gene Symbol: DNAJB11
DNAJB11
Q9UBS4 DnaJ heat shock protein family (Hsp40) member B11 18 0.751 0.346 0.23 0.010 None 1.000 1 0 2017 2017