Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 56897
Gene Symbol: WRNIP1
WRNIP1 		Q96S55 WRN helicase interacting protein 1 Enzyme 2 0.931 0.115 2.5E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 26054
Gene Symbol: SENP6
SENP6 		Q9GZR1 SUMO specific peptidase 6 Enzyme 16 0.760 0.269 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 791254
Gene Symbol: EDS8
EDS8 		Ehlers-Danlos syndrome, type VIII 7 0.839 0.269 0.010 None 1.000 1 0 1991 1991
Entrez Id: 199953
Gene Symbol: TMEM201
TMEM201 		Q5SNT2 transmembrane protein 201 21 0.729 0.346 0.99 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3008
Gene Symbol: H1-4
H1-4 		P10412 H1.4 linker histone, cluster member Nucleic acid binding 34 0.682 0.385 0.19 0.010 None 1.000 1 0 2019 2019
Entrez Id: 83985
Gene Symbol: SPNS1
SPNS1 		Q9H2V7 sphingolipid transporter 1 (putative) Transporter 38 0.716 0.385 2.0E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 23404
Gene Symbol: EXOSC2
EXOSC2 		Q13868 exosome component 2 Enzyme 37 0.711 0.462 2.9E-06 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57132
Gene Symbol: CHMP1B
CHMP1B 		Q7LBR1 charged multivesicular body protein 1B Transporter 24 0.736 0.462 0.73 0.010 None 1.000 1 0 2016 2016
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN 		Q9H040 SprT-like N-terminal domain 44 0.691 0.500 0.97 0.030 None 1.000 3 0 2014 2019
Entrez Id: 54840
Gene Symbol: APTX
APTX 		Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9400
Gene Symbol: RECQL5
RECQL5 		O94762 RecQ like helicase 5 Enzyme 28 0.682 0.500 3.2E-18 0.010 None < 0.001 1 0 2016 2016
Entrez Id: 10428
Gene Symbol: CFDP1
CFDP1 		Q9UEE9 craniofacial development protein 1 71 0.619 0.615 3.7E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 23415
Gene Symbol: KCNH4
KCNH4 		Q9UQ05 potassium voltage-gated channel subfamily H member 4 Ion channel 61 0.603 0.615 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 260402
Gene Symbol: IS1
IS1 		Adolescent idiopathic scoliosis 83 0.593 0.615 0.010 None 1.000 1 0 2019 2019
Entrez Id: 64750
Gene Symbol: SMURF2
SMURF2 		Q9HAU4 SMAD specific E3 ubiquitin protein ligase 2 Enzyme 59 0.623 0.615 0.87 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7156
Gene Symbol: TOP3A
TOP3A 		Q13472 DNA topoisomerase III alpha Enzyme 52 0.656 0.615 5.1E-11 0.010 None 1.000 1 0 2009 2009
Entrez Id: 131096
Gene Symbol: KCNH8
KCNH8 		Q96L42 potassium voltage-gated channel subfamily H member 8 Ion channel 62 0.603 0.654 2.3E-10 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4654
Gene Symbol: MYOD1
MYOD1 		P15172 myogenic differentiation 1 Transcription factor 106 0.569 0.654 0.15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 55556
Gene Symbol: ENOSF1
ENOSF1 		Q7L5Y1 enolase superfamily member 1 Enzyme 59 0.617 0.654 9.0E-19 0.010 None 1.000 1 0 2013 2013
Entrez Id: 55651
Gene Symbol: NHP2
NHP2 		Q9NX24 NHP2 ribonucleoprotein Nucleic acid binding 91 0.623 0.654 5.0E-02 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5831
Gene Symbol: PYCR1
PYCR1 		P32322 pyrroline-5-carboxylate reductase 1 126 0.570 0.654 2.0E-04 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5928
Gene Symbol: RBBP4
RBBP4 		Q09028 RB binding protein 4, chromatin remodeling factor 45 0.644 0.654 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8451
Gene Symbol: CUL4A
CUL4A 		Q13619 cullin 4A Enzyme 79 0.597 0.654 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 493856
Gene Symbol: CISD2
CISD2 		Q8N5K1 CDGSH iron sulfur domain 2 106 0.590 0.692 0.42 0.050 None 0.800 5 0 2009 2019
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2 		O43464 HtrA serine peptidase 2 151 0.542 0.692 3.6E-03 0.040 None 1.000 4 0 2013 2018