Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.060 None 1.000 6 0 2009 2019
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
Q99572 purinergic receptor P2X 7 Ion channel 337 0.450 0.808 3.3E-11 0.030 None 1.000 3 0 2009 2019
Entrez Id: 5024
Gene Symbol: P2RX3
P2RX3
P56373 purinergic receptor P2X 3 Ion channel 125 0.565 0.769 1.0E-06 0.060 None 1.000 6 0 2010 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.050 None 1.000 5 0 2010 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.040 None 1.000 4 0 2010 2018
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.040 None 1.000 4 0 2010 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.030 None 1.000 3 0 2010 2018
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.030 None 1.000 3 0 2010 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2010 2019
Entrez Id: 23101
Gene Symbol: MCF2L2
MCF2L2
Q86YR7 MCF.2 cell line derived transforming sequence-like 2 Signaling 60 0.628 0.577 1.2E-24 0.020 None 1.000 2 0 2010 2017
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.010 None 1.000 1 0 2010 2010
Entrez Id: 796
Gene Symbol: CALCA
CALCA
P01258 P06881 calcitonin related polypeptide alpha Signaling 467 0.416 0.923 1.6E-02 0.030 None 1.000 3 0 2011 2019
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.010 None 1.000 1 0 2011 2011
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
P25106 atypical chemokine receptor 3 G-protein coupled receptor 400 0.428 0.885 0.39 0.010 None 1.000 1 0 2011 2011
Entrez Id: 680
Gene Symbol: BRS3
BRS3
P32247 bombesin receptor subtype 3 G-protein coupled receptor 261 0.474 0.846 0.95 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6754
Gene Symbol: SSTR4
SSTR4
P31391 somatostatin receptor 4 G-protein coupled receptor 273 0.469 0.846 3.7E-13 0.010 None 1.000 1 0 2011 2011
Entrez Id: 2866
Gene Symbol: GPR42
GPR42
O15529 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor 255 0.475 0.846 5.1E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 552
Gene Symbol: AVPR1A
AVPR1A
P37288 arginine vasopressin receptor 1A G-protein coupled receptor 51 0.663 0.500 6.9E-07 0.010 None 1.000 1 0 2011 2011
Entrez Id: 156
Gene Symbol: GRK2
GRK2
P25098 G protein-coupled receptor kinase 2 Kinase 159 0.532 0.654 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 151
Gene Symbol: ADRA2B
ADRA2B
P18089 adrenoceptor alpha 2B G-protein coupled receptor 296 0.465 0.846 4.5E-06 0.010 None 1.000 1 0 2011 2011
Entrez Id: 148
Gene Symbol: ADRA1A
ADRA1A
P35348 adrenoceptor alpha 1A G-protein coupled receptor 294 0.462 0.846 3.4E-07 0.010 None 1.000 1 0 2011 2011
Entrez Id: 10663
Gene Symbol: CXCR6
CXCR6
O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 325 0.448 0.885 5.7E-05 0.010 None 1.000 1 0 2011 2011
Entrez Id: 9170
Gene Symbol: LPAR2
LPAR2
Q9HBW0 lysophosphatidic acid receptor 2 G-protein coupled receptor 285 0.463 0.846 3.7E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.020 None 1.000 2 0 2012 2015