Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.948 58 1 1998 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.200 None 1.000 12 1 1995 2019
Entrez Id: 2896
Gene Symbol: GRN
GRN 		P28799 granulin precursor 412 0.435 0.846 7.0E-02 0.180 None 1.000 8 0 2009 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.080 None 1.000 8 4 2004 2019
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2 		Q13753 laminin subunit gamma 2 Enzyme modulator 602 0.389 0.923 2.9E-12 0.060 None 0.833 6 0 2016 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.060 None 0.833 6 0 2016 2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL 		P07196 neurofilament light 247 0.488 0.769 0.050 None 1.000 5 0 2017 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.040 None 1.000 4 0 2014 2019
Entrez Id: 6709
Gene Symbol: SPTAN1
SPTAN1 		Q13813 spectrin alpha, non-erythrocytic 1 82 0.601 0.615 1.00 0.140 None 1.000 4 0 2012 2017
Entrez Id: 3064
Gene Symbol: HTT
HTT 		P42858 huntingtin 188 0.548 0.654 1.00 0.130 None 1.000 3 0 1997 2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.030 None 1.000 3 0 2011 2018
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.030 None 1.000 3 0 2011 2017
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2 		P18065 insulin like growth factor binding protein 2 Enzyme modulator 241 0.478 0.769 0.12 0.030 None 1.000 3 0 2015 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.130 None 1.000 3 1 2012 2016
Entrez Id: 5354
Gene Symbol: PLP1
PLP1 		P60201 proteolipid protein 1 Cellular structure 160 0.543 0.769 0.93 0.030 None 0.667 3 0 2001 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2001 2019
Entrez Id: 6653
Gene Symbol: SORL1
SORL1 		Q92673 sortilin related receptor 1 Transporter 103 0.582 0.692 7.7E-11 0.020 None 1.000 2 3 2014 2016
Entrez Id: 9211
Gene Symbol: LGI1
LGI1 		O95970 leucine rich glioma inactivated 1 118 0.568 0.731 1.00 0.020 None 1.000 2 0 2017 2019
Entrez Id: 23065
Gene Symbol: EMC1
EMC1 		Q8N766 ER membrane protein complex subunit 1 38 0.700 0.462 6.7E-26 0.100 None 1.000 2 1 2016 2017
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.020 None 1.000 2 0 2017 2019
Entrez Id: 8540
Gene Symbol: AGPS
AGPS 		O00116 alkylglycerone phosphate synthase 38 0.670 0.538 1.00 0.020 None 1.000 2 0 2013 2018
Entrez Id: 1203
Gene Symbol: CLN5
CLN5 		O75503 CLN5 intracellular trafficking protein 43 0.705 0.269 1.7E-08 0.020 None 0.500 2 0 2004 2018
Entrez Id: 274
Gene Symbol: BIN1
BIN1 		O00499 bridging integrator 1 163 0.550 0.692 0.78 0.020 None 1.000 2 0 2016 2019
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72 		Q96LT7 C9orf72-SMCR8 complex subunit 258 0.496 0.769 1.1E-06 0.120 None 1.000 2 0 2012 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2017 2017