Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.110 None 1.000 1 1 2017 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.100 None 1.000 19 0 1999 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 16 1 2000 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.040 None 1.000 4 0 1995 2002
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.040 None 0.750 4 0 1995 2007
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Q8WXI7 mucin 16, cell surface associated 236 0.479 0.808 8.3E-112 0.020 None 1.000 2 0 2002 2013
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.010 None 1.000 1 0 2012 2012
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.010 None 1.000 1 0 2017 2017
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
P24864 cyclin E1 Enzyme modulator 133 0.538 0.731 0.97 0.010 None 1.000 1 0 2003 2003
Entrez Id: 55259
Gene Symbol: CASC1
CASC1
Q6TDU7 cancer susceptibility 1 16 0.760 0.269 3.9E-14 0.010 None 1.000 1 0 2000 2000
Entrez Id: 4771
Gene Symbol: NF2
NF2
P35240 neurofibromin 2 312 0.468 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2016 2016
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
P14902 indoleamine 2,3-dioxygenase 1 295 0.454 0.846 3.3E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29893
Gene Symbol: PSMC3IP
PSMC3IP
Q9P2W1 PSMC3 interacting protein Nucleic acid binding 53 0.659 0.500 3.8E-05 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2014 2014
Entrez Id: 10519
Gene Symbol: CIB1
CIB1
Q99828 calcium and integrin binding 1 275 0.458 0.769 3.3E-04 0.010 None 1.000 1 0 2007 2007
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.010 None 1.000 1 0 2007 2007