Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 17 0 2008 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.040 None 1.000 4 0 2017 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 16 0 2011 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.090 None 0.889 9 0 2014 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2015 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.070 None 0.857 7 1 2004 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.050 None 1.000 5 0 1992 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 0.941 17 0 2007 2020
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 Signaling 1028 0.330 0.962 0.83 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.010 None 1.000 1 0 2004 2004
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.050 None 1.000 5 0 2013 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.030 None 0.667 3 0 2010 2017
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.020 None 1.000 2 1 2014 2016
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None < 0.001 1 1 2014 2014
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.040 None 1.000 4 0 2014 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 1.000 13 0 1999 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.040 None 1.000 4 0 1994 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.050 None 1.000 5 0 2010 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.040 None 1.000 4 0 2002 2015
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.040 None 1.000 4 0 2003 2012
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.020 None 1.000 2 0 2017 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.090 None 1.000 9 0 2005 2017