Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.600 None 0.983 1494 32 1988 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.800 None 0.944 607 32 1989 2020
Entrez Id: 8897
Gene Symbol: MTMR3
MTMR3
Q13615 myotubularin related protein 3 Enzyme 41 0.682 0.462 1.00 0.110 None 1.000 1 19 2011 2011
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.400 None 0.971 68 18 2001 2019
Entrez Id: 150280
Gene Symbol: HORMAD2
HORMAD2
Q8N7B1 HORMA domain containing 2 22 0.716 0.385 7.1E-05 0.120 None 1.000 2 18 2011 2014
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 75 0.644 0.423 0.14 0.500 None 1.000 27 16 2008 2018
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 110 0.588 0.692 1.4E-07 0.500 None 1.000 54 15 2008 2020
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.932 88 12 2001 2019
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 110 0.593 0.577 2.1E-06 0.500 None 0.934 61 11 2008 2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.600 None 0.947 38 11 2005 2019
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.020 None 1.000 2 10 2009 2011
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.100 None 0.948 58 9 2001 2019
Entrez Id: 8840
Gene Symbol: CCN4
CCN4
O95388 cellular communication network factor 4 Signaling 114 0.554 0.692 6.4E-07 0.050 None 1.000 5 9 2003 2017
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
Q96KA5 CLPTM1 like Enzyme 110 0.551 0.654 4.4E-05 0.500 None 0.978 45 8 2008 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.875 32 8 2004 2019
Entrez Id: 4585
Gene Symbol: MUC4
MUC4
Q99102 mucin 4, cell surface associated 183 0.506 0.769 2.8E-54 0.060 None 1.000 6 8 1996 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 0.959 49 7 1989 2019
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.100 None 0.971 34 7 2006 2019
Entrez Id: 9156
Gene Symbol: EXO1
EXO1
Q9UQ84 exonuclease 1 Enzyme 87 0.578 0.692 8.1E-13 0.030 None 1.000 3 7 2008 2014
Entrez Id: 101929664
Gene Symbol: HORMAD2-AS1
HORMAD2-AS1
HORMAD2 and MTMR3 antisense RNA 1 7 0.839 0.308 0.100 None 1.000 1 7 2011 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.400 None 0.961 129 6 1989 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.600 None 1.000 48 6 2002 2020
Entrez Id: 328
Gene Symbol: APEX1
APEX1
P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 305 0.458 0.846 1.9E-07 0.100 None 0.879 33 6 2003 2019
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.400 None 0.964 28 6 1977 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.100 None 1.000 21 6 2001 2019