Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.700 None 1.000 101 11 1998 2019
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.700 None 1.000 92 8 2001 2019
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.700 None 1.000 22 2 1992 2019
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Q99497 Parkinsonism associated deglycase Enzyme 161 0.535 0.808 0.75 0.600 None 1.000 30 3 2001 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.530 None 1.000 7 0 1997 2018
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.500 None 0.975 120 5 1998 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.500 None 0.965 85 2 1999 2018
Entrez Id: 23400
Gene Symbol: ATP13A2
ATP13A2
Q9NQ11 ATPase cation transporting 13A2 160 0.566 0.577 9.0E-09 0.500 None 1.000 34 0 2003 2019
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.500 None 1.000 21 4 2004 2020
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.500 None 0.952 21 3 2004 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.500 None 1.000 4 0 1997 2011
Entrez Id: 2936
Gene Symbol: GSR
GSR
P00390 glutathione-disulfide reductase Enzyme 206 0.494 0.846 1.3E-06 0.500 None 1.000 2 0 2011 2012
Entrez Id: 8575
Gene Symbol: PRKRA
PRKRA
O75569 protein activator of interferon induced protein kinase EIF2AK2 Kinase 113 0.579 0.615 0.42 0.480 None 1.000 8 0 2008 2018
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3
P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 174 0.544 0.615 1.00 0.480 None 1.000 8 0 2004 2016
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1
Q14203 dynactin subunit 1 Chaperone 116 0.597 0.500 8.4E-02 0.440 None 1.000 5 1 2009 2018
Entrez Id: 55532
Gene Symbol: SLC30A10
SLC30A10
Q6XR72 solute carrier family 30 member 10 Transporter 120 0.578 0.654 0.98 0.430 None 1.000 4 0 2013 2019
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2
Q05940 solute carrier family 18 member A2 Transporter 150 0.554 0.769 7.6E-02 0.430 None 1.000 4 0 2006 2019
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.400 None 0.967 92 7 2004 2020
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.400 None 0.984 64 0 1997 2020
Entrez Id: 391356
Gene Symbol: PTRHD1
PTRHD1
Q6GMV3 peptidyl-tRNA hydrolase domain containing 1 5 0.890 0.154 4.6E-07 0.320 moderate 1.000 3 1 2017 2018
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
O43464 HtrA serine peptidase 2 151 0.542 0.692 3.6E-03 0.320 None 1.000 3 0 2015 2019
Entrez Id: 1644
Gene Symbol: DDC
DDC
P20711 dopa decarboxylase 164 0.535 0.769 3.8E-08 0.310 None 1.000 2 0 2006 2017
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin Signaling 103 0.603 0.577 1.5E-02 0.310 None 1.000 2 0 2010 2016
Entrez Id: 1130
Gene Symbol: LYST
LYST
Q99698 lysosomal trafficking regulator 114 0.621 0.692 1.5E-02 0.300 strong 1.000 3 0 2002 2014
Entrez Id: 5617
Gene Symbol: PRL
PRL
P01236 prolactin Signaling 506 0.406 0.885 2.9E-07 0.300 None 1.000 1 0 1975 1975