Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 0.955 22 0 1998 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.100 None 0.900 10 0 2004 2019
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.060 None 0.833 6 0 2011 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 1995 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.040 None 0.750 4 0 2000 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.030 None 1.000 3 0 2004 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.030 None 1.000 3 0 2009 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.030 None 1.000 3 0 2013 2017
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.030 None 0.667 3 0 1999 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
P23771 GATA binding protein 3 429 0.415 0.846 0.90 0.020 None 1.000 2 0 2018 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.020 None 1.000 2 0 2019 2019
Entrez Id: 27324
Gene Symbol: TOX3
TOX3
O15405 TOX high mobility group box family member 3 49 0.636 0.538 1.00 0.020 None 1.000 2 0 2011 2013
Entrez Id: 60500
Gene Symbol: BRCA3
BRCA3
breast cancer 3 27 0.705 0.269 0.020 None 1.000 2 0 2013 2014
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.020 None 1.000 2 0 2016 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.020 None 1.000 2 0 2016 2017
Entrez Id: 6901
Gene Symbol: TAZ
TAZ
Q16635 tafazzin Enzyme 252 0.477 0.808 0.73 0.020 None 1.000 2 0 2016 2017
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1
O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.020 None 1.000 2 0 2004 2017
Entrez Id: 6047
Gene Symbol: RNF4
RNF4
P78317 ring finger protein 4 27 0.705 0.462 0.80 0.010 None 1.000 1 0 2000 2000
Entrez Id: 57697
Gene Symbol: FANCM
FANCM
Q8IYD8 FA complementation group M Enzyme 147 0.543 0.731 2.4E-15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.010 None 1.000 1 0 2016 2016
Entrez Id: 574456
Gene Symbol: MIR497
MIR497
microRNA 497 116 0.539 0.808 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 574450
Gene Symbol: MIR493
MIR493
microRNA 493 52 0.626 0.538 0.010 None 1.000 1 0 2010 2010
Entrez Id: 56946
Gene Symbol: EMSY
EMSY
Q7Z589 EMSY transcriptional repressor, BRCA2 interacting 52 0.628 0.423 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 558
Gene Symbol: AXL
AXL
P30530 AXL receptor tyrosine kinase Kinase 203 0.489 0.615 1.3E-02 0.010 None 1.000 1 0 2017 2017