Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 270
Gene Symbol: AMPD1
AMPD1 		P23109 adenosine monophosphate deaminase 1 Enzyme 93 0.573 0.692 1.9E-21 0.010 None 1.000 1 0 2004 2004
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 979 0.328 0.923 1.0E-37 0.080 None 1.000 8 0 2010 2019
Entrez Id: 5104
Gene Symbol: SERPINA5
SERPINA5 		P05154 serpin family A member 5 Enzyme modulator 176 0.507 0.808 6.2E-09 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 668 0.370 0.923 2.4E-07 0.060 None 1.000 6 0 2012 2019
Entrez Id: 4053
Gene Symbol: LTBP2
LTBP2 		Q14767 latent transforming growth factor beta binding protein 2 Calcium-binding protein 65 0.572 0.692 7.4E-04 0.010 None 1.000 1 0 2012 2012
Entrez Id: 366
Gene Symbol: AQP9
AQP9 		O43315 aquaporin 9 Ion channel 84 0.565 0.808 0.24 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4054
Gene Symbol: LTBP3
LTBP3 		Q9NS15 latent transforming growth factor beta binding protein 3 Calcium-binding protein 91 0.564 0.846 0.69 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 555 0.380 0.885 0.50 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		P13501 C-C motif chemokine ligand 5 Signaling 460 0.403 0.885 1.8E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A 		microRNA 18a 139 0.520 0.846 0.010 None 1.000 1 0 2016 2016
Entrez Id: 6019
Gene Symbol: RLN2
RLN2 		P04090 relaxin 2 Signaling 53 0.626 0.615 9.0E-04 0.090 None 1.000 9 0 2017 2020
Entrez Id: 2157
Gene Symbol: F8
F8 		P00451 coagulation factor VIII Enzyme 127 0.542 0.769 1.00 0.090 None 1.000 9 0 2017 2020
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2 		P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 263 0.469 0.846 0.84 0.070 None 1.000 7 0 2017 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3 		P17931 galectin 3 Signaling 524 0.392 0.846 2.3E-05 0.070 None 1.000 7 0 2017 2020
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 436 0.397 0.846 0.34 0.060 None 1.000 6 0 2017 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		P80188 lipocalin 2 Enzyme 463 0.405 0.885 1.1E-09 0.060 None 1.000 6 0 2017 2019
Entrez Id: 551
Gene Symbol: AVP
AVP 		P01185 arginine vasopressin Signaling 378 0.437 0.846 7.4E-02 0.060 None 1.000 6 0 2017 2019
Entrez Id: 59272
Gene Symbol: ACE2
ACE2 		Q9BYF1 angiotensin I converting enzyme 2 Enzyme 238 0.477 0.769 1.00 0.050 None 1.000 5 0 2017 2019
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.050 None 1.000 5 0 2017 2019
Entrez Id: 94025
Gene Symbol: MUC16
MUC16 		Q8WXI7 mucin 16, cell surface associated 228 0.479 0.808 8.3E-112 0.050 None 1.000 5 0 2017 2020
Entrez Id: 4879
Gene Symbol: NPPB
NPPB 		P16860 natriuretic peptide B 128 0.513 0.808 9.9E-06 0.040 None 1.000 4 0 2017 2020
Entrez Id: 9518
Gene Symbol: GDF15
GDF15 		Q99988 growth differentiation factor 15 Signaling 374 0.429 0.808 3.0E-07 0.030 None 1.000 3 0 2017 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 316 0.436 0.808 3.9E-03 0.030 None 0.667 3 0 2017 2017
Entrez Id: 5179
Gene Symbol: PENK
PENK 		P01210 proenkephalin Signaling 92 0.560 0.808 2.1E-04 0.020 None 1.000 2 0 2017 2017