Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.800 strong 1.000 15 2 2003 2018
Entrez Id: 55835
Gene Symbol: CENPJ
CENPJ 		Q9HC77 centromere protein J Enzyme 150 0.546 0.846 2.1E-27 0.710 None 1.000 1 0 2010 2010
Entrez Id: 5116
Gene Symbol: PCNT
PCNT 		O95613 pericentrin 156 0.564 0.808 4.0E-58 0.550 strong 1.000 6 0 2008 2011
Entrez Id: 10733
Gene Symbol: PLK4
PLK4 		O00444 polo like kinase 4 Kinase 135 0.551 0.731 7.1E-06 0.510 None 1.000 3 0 2014 2017
Entrez Id: 10293
Gene Symbol: TRAIP
TRAIP 		Q9BWF2 TRAF interacting protein 77 0.644 0.654 1.6E-05 0.510 strong 1.000 2 0 2016 2018
Entrez Id: 1062
Gene Symbol: CENPE
CENPE 		Q02224 centromere protein E Cellular structure 78 0.636 0.692 0.24 0.510 None 1.000 1 0 2014 2014
Entrez Id: 84126
Gene Symbol: ATRIP
ATRIP 		Q8WXE1 ATR interacting protein 54 0.666 0.692 2.0E-05 0.510 limited 1.000 1 0 2012 2012
Entrez Id: 22995
Gene Symbol: CEP152
CEP152 		O94986 centrosomal protein 152 Signaling 66 0.653 0.500 2.7E-27 0.410 None 1.000 1 1 2011 2011
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.320 strong 1.000 3 0 2001 2015
Entrez Id: 1763
Gene Symbol: DNA2
DNA2 		P51530 DNA replication helicase/nuclease 2 71 0.626 0.731 1.3E-18 0.320 limited 1.000 2 0 2014 2019
Entrez Id: 10785
Gene Symbol: WDR4
WDR4 		P57081 WD repeat domain 4 Nucleic acid binding 72 0.653 0.538 1.4E-08 0.310 moderate 1.000 2 0 2015 2018
Entrez Id: 5932
Gene Symbol: RBBP8
RBBP8 		Q99708 RB binding protein 8, endonuclease Transcription factor 110 0.584 0.808 3.1E-12 0.310 None 1.000 1 0 2011 2011
Entrez Id: 4998
Gene Symbol: ORC1
ORC1 		Q13415 origin recognition complex subunit 1 Nucleic acid binding 103 0.595 0.654 1.7E-14 0.310 strong 1.000 1 0 2011 2011
Entrez Id: 5000
Gene Symbol: ORC4
ORC4 		O43929 origin recognition complex subunit 4 Nucleic acid binding 75 0.612 0.654 7.6E-13 0.300 strong 1.000 1 0 2011 2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.300 strong 1.000 1 0 1996 1996
Entrez Id: 51053
Gene Symbol: GMNN
GMNN 		O75496 geminin DNA replication inhibitor 153 0.554 0.808 0.11 0.300 strong 1.000 1 0 2015 2015
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4 		Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.300 strong 1.000 1 0 2014 2014
Entrez Id: 81620
Gene Symbol: CDT1
CDT1 		Q9H211 chromatin licensing and DNA replication factor 1 91 0.597 0.731 2.6E-10 0.300 strong 1.000 1 0 2011 2011
Entrez Id: 990
Gene Symbol: CDC6
CDC6 		Q99741 cell division cycle 6 130 0.552 0.731 1.1E-09 0.300 None 1.000 1 0 2012 2012
Entrez Id: 23594
Gene Symbol: ORC6
ORC6 		Q9Y5N6 origin recognition complex subunit 6 Nucleic acid binding 80 0.628 0.577 3.4E-07 0.300 strong 1.000 1 0 2011 2011
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A 		Q9Y6K1 DNA methyltransferase 3 alpha 350 0.445 0.846 7.4E-39 0.300 strong 1.000 1 0 2018 2018
Entrez Id: 1063
Gene Symbol: CENPF
CENPF 		P49454 centromere protein F 76 0.601 0.654 1.9E-36 0.300 strong 1.000 1 0 2015 2015
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.200 None 1.000 2 0 2011 2012
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.200 None 1.000 1 0 2018 2018
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.200 None 1.000 1 0 2004 2004