Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11005
Gene Symbol: SPINK5
SPINK5
Q9NQ38 serine peptidase inhibitor Kazal type 5 Enzyme modulator 93 0.604 0.654 4.8E-28 1.000 strong 0.982 57 19 2000 2019
Entrez Id: 6768
Gene Symbol: ST14
ST14
Q9Y5Y6 suppression of tumorigenicity 14 Enzyme 170 0.514 0.769 0.56 0.300 None 1.000 1 0 2010 2010
Entrez Id: 25818
Gene Symbol: KLK5
KLK5
Q9Y337 kallikrein related peptidase 5 Enzyme 59 0.623 0.462 7.0E-03 0.070 None 1.000 7 0 2014 2019
Entrez Id: 5650
Gene Symbol: KLK7
KLK7
P49862 kallikrein related peptidase 7 Enzyme 62 0.610 0.615 6.5E-04 0.050 None 1.000 5 0 2013 2018
Entrez Id: 2312
Gene Symbol: FLG
FLG
P20930 filaggrin Cellular structure 173 0.525 0.846 2.9E-04 0.030 None 1.000 3 0 2005 2011
Entrez Id: 1828
Gene Symbol: DSG1
DSG1
Q02413 desmoglein 1 Cell adhesion 81 0.606 0.538 0.93 0.020 None 1.000 2 0 2005 2009
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
P08246 elastase, neutrophil expressed Enzyme 346 0.447 0.846 1.2E-03 0.020 None 1.000 2 0 2010 2014
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1
O60500 NPHS1 adhesion molecule, nephrin 87 0.597 0.615 2.5E-14 0.020 None 1.000 2 0 2007 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 2015 2018
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2
Q9NP85 NPHS2 stomatin family member, podocin Enzyme modulator 86 0.576 0.538 7.2E-09 0.020 None 1.000 2 0 2007 2012
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin Signaling 454 0.437 0.846 7.4E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5653
Gene Symbol: KLK6
KLK6
Q92876 kallikrein related peptidase 6 Enzyme 99 0.575 0.654 6.0E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5460
Gene Symbol: POU5F1
POU5F1
Q01860 POU class 5 homeobox 1 328 0.441 0.846 0.95 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5266
Gene Symbol: PI3
PI3
P19957 peptidase inhibitor 3 Enzyme modulator 92 0.570 0.692 0.17 0.010 None 1.000 1 0 2004 2004
Entrez Id: 50616
Gene Symbol: IL22
IL22
Q9GZX6 interleukin 22 551 0.393 0.885 1.9E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 28471
Gene Symbol: IGHV1-12
IGHV1-12
immunoglobulin heavy variable 1-12 (pseudogene) 89 0.569 0.654 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.010 None 1.000 1 0 2012 2012
Entrez Id: 43847
Gene Symbol: KLK14
KLK14
Q9P0G3 kallikrein related peptidase 14 Enzyme 33 0.711 0.385 2.0E-08 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4282
Gene Symbol: MIF
MIF
P14174 macrophage migration inhibitory factor 455 0.412 0.885 1.2E-02 0.010 None 1.000 1 1 2016 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.010 None 1.000 1 0 2014 2014
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
O14543 suppressor of cytokine signaling 3 Enzyme modulator 375 0.434 0.808 0.75 0.010 None 1.000 1 0 2016 2016
Entrez Id: 79671
Gene Symbol: NLRX1
NLRX1
Q86UT6 NLR family member X1 Enzyme 51 0.641 0.654 7.7E-31 0.010 None 1.000 1 0 2018 2018