Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.040 None 1.000 4 4 1995 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 5 2011 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 0 2008 2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.010 None 1.000 1 0 1997 1997
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2020 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.020 None 1.000 2 0 2004 2019
Entrez Id: 5111
Gene Symbol: PCNA
PCNA 		P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 2006 2006
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.020 None 1.000 2 1 2007 2011
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		O60760 hematopoietic prostaglandin D synthase 570 0.388 0.923 1.8E-06 0.020 None 1.000 2 0 2004 2007
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.020 None 1.000 2 0 2004 2019
Entrez Id: 196
Gene Symbol: AHR
AHR 		P35869 aryl hydrocarbon receptor Transcription factor 532 0.410 0.923 1.00 0.010 None 1.000 1 1 2004 2004
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.010 None 1.000 1 3 2006 2006
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 1.000 definitive 0.935 62 36 1977 2017
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.957 47 5 2002 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.020 None 1.000 2 0 2008 2011
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.010 None 1.000 1 0 2018 2018
Entrez Id: 613
Gene Symbol: BCR
BCR 		P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.010 None 1.000 1 0 2014 2014
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 345 0.445 0.846 1.6E-07 0.100 None 0.900 10 2 2004 2016
Entrez Id: 5888
Gene Symbol: RAD51
RAD51 		Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.090 None 1.000 9 4 2006 2016
Entrez Id: 328
Gene Symbol: APEX1
APEX1 		P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 305 0.458 0.846 1.9E-07 0.040 None 0.750 4 3 2003 2014